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Chchd2l2 Gene Detail
Summary
  • Symbol
    Chchd2l2
  • Name
    coiled-coil-helix-coiled-coil-helix domain containing 2 like 2
  • Synonyms
    2410018M08Rik, Zbed5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919220
    NCBI Gene: 71970
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:129924564-129932464 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 68.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    341 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919220
 protein coding gene Chr5:129924564-129937350 (+)
129S1/SvImJ ENSMUSG00200044199
 protein coding gene Chr5:123670057-123677955 (+)
A/J ENSMUSG00195048496
 protein coding gene Chr5:123204180-123212052 (+)
AKR/J ENSMUSG00220049157
 protein coding gene Chr5:122680767-122688671 (+)
BALB/cJ ENSMUSG00180036739
 protein coding gene Chr5:123311552-123319423 (+)
C3H/HeJ ENSMUSG00175032659
 protein coding gene Chr5:125280402-125288302 (+)
C57BL/6NJ ENSMUSG00215048157
 protein coding gene Chr5:123342509-123350409 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027790
 protein coding gene Chr5:122727506-122736501 (+)
CAST/EiJ ENSTCUG00005009267
 protein coding gene Chr5:122564017-122571938 (+)
CBA/J ENSMUSG00210006802
 protein coding gene Chr5:124031072-124038972 (+)
DBA/2J ENSMUSG00185007069
 protein coding gene Chr5:127083024-127090929 (+)
FVB/NJ ENSMUSG00205046097
 protein coding gene Chr5:122964242-122972141 (+)
JF1/MsJ ENSUMUG00000038555
 protein coding gene Chr5:129967574-129975973 (+)
LP/J ENSMUSG00230041211
 protein coding gene Chr5:131185975-131193873 (+)
NOD/ShiLtJ ENSMUSG00190029524
 protein coding gene Chr5:122985725-122993622 (+)
NZO/HlLtJ ENSMUSG00225014131
 protein coding gene Chr5:138881459-138889357 (+)
PWK/PhJ ENSLUMG00010017555
 protein coding gene Chr5:121855866-121864263 (+)
SPRET/EiJ ENSMSPG00010029136
 protein coding gene Chr5:125273639-125281201 (+)
WSB/EiJ ENSIUOG00005029146
 protein coding gene Chr5:125664939-125672839 (+)



Homology
more
  • Human Ortholog
    ZBED5, zinc finger BED-type containing 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBED5, zinc finger BED-type containing 5
  • Synonyms
    Buster1
  • Links
    NCBI Gene ID: 58486
    UniProt: Q49AG3

  • Chr Location
    11p15.4; chr11:10812074-10858796 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Chchd2l2
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    31 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    23
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034173 Ensembl Gene Model | MGI Sequence Detail 7901 C57BL/6J ±  kb
transcript ENSMUST00000041466 Ensembl | MGI Sequence Detail 2492 Not Applicable  
polypeptide ENSMUSP00000044533 Ensembl | MGI Sequence Detail 756 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR055304 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2/10-like
    IPR012337 Ribonuclease H-like superfamily
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 5
Other
Accession IDs
less
MGI:6865767, MGI:7378507, MGI:8331709
References
more
  • Summaries
    All 36
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory