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Zbtb43 Gene Detail
Summary
  • Symbol
    Zbtb43
  • Name
    zinc finger and BTB domain containing 43
  • Synonyms
    1700010E06Rik, mKIAA0414, Zfp297b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919084
    NCBI Gene: 71834
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:33340299-33358571 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.46 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    408 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919084
 protein coding gene Chr2:33340299-33358592 (-)
129S1/SvImJ ENSMUSG00200050312
 protein coding gene Chr2:30312779-30331054 (-)
A/J ENSMUSG00195037761
 protein coding gene Chr2:30417011-30435271 (-)
AKR/J ENSMUSG00220040225
 protein coding gene Chr2:30534981-30553245 (-)
BALB/cJ ENSMUSG00180048338
 protein coding gene Chr2:30429070-30447346 (-)
C3H/HeJ ENSMUSG00175039392
 protein coding gene Chr2:30395458-30413730 (-)
C57BL/6NJ ENSMUSG00215046066
 protein coding gene Chr2:30460962-30479235 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023461
 protein coding gene Chr2:29348455-29367809 (-)
CAST/EiJ ENSTCUG00005051669
 protein coding gene Chr2:30142238-30160502 (-)
CBA/J ENSMUSG00210047562
 protein coding gene Chr2:30467982-30486256 (-)
DBA/2J ENSMUSG00185044600
 protein coding gene Chr2:30330158-30348417 (-)
FVB/NJ ENSMUSG00205032803
 protein coding gene Chr2:30176548-30194808 (-)
JF1/MsJ ENSUMUG00000051928
 protein coding gene Chr2:30223422-30241560 (-)
LP/J ENSMUSG00230039007
 protein coding gene Chr2:32248256-32266527 (-)
NOD/ShiLtJ ENSMUSG00190035985
 protein coding gene Chr2:30431501-30449760 (-)
NZO/HlLtJ ENSMUSG00225008869
 protein coding gene Chr2:40002390-40020711 (-)
PWK/PhJ ENSLUMG00010041990
 protein coding gene Chr2:30320684-30338811 (-)
SPRET/EiJ ENSMSPG00010041431
 protein coding gene Chr2:31022372-31037871 (-)
WSB/EiJ ENSIUOG00005039209
 protein coding gene Chr2:30279969-30298244 (-)



Homology
more
  • Human Ortholog
    ZBTB43, zinc finger and BTB domain containing 43
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB43, zinc finger and BTB domain containing 43
  • Synonyms
    ZBTB22B, ZNF297B, ZNF-X
  • Links
    NCBI Gene ID: 23099
    UniProt: O43298

  • Chr Location
    9q33.3; chr9:126804072-126838210 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    731
  • Tissues
    106
  • cDNA Data
    64
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026788 Ensembl Gene Model | MGI Sequence Detail 18273 C57BL/6J ±  kb
    transcript ENSMUST00000095035 Ensembl | MGI Sequence Detail 4925 Not Applicable  
    polypeptide ENSMUSP00000092645 Ensembl | MGI Sequence Detail 504 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 65
      cDNA 64
      Primer pair 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 6
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory