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Fbxo9 Gene Detail
Summary
  • Symbol
    Fbxo9
  • Name
    F-box protein 9
  • Synonyms
    9030401P18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918788
    NCBI Gene: 71538
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:77988781-78016347 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 43.53 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    810 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918788
 protein coding gene Chr9:77988781-78016347 (-)
129S1/SvImJ ENSMUSG00200018600
 protein coding gene Chr9:75139281-75166848 (-)
A/J ENSMUSG00195010162
 protein coding gene Chr9:74906710-74934274 (-)
AKR/J ENSMUSG00220014508
 protein coding gene Chr9:75039517-75067078 (-)
BALB/cJ ENSMUSG00180016287
 protein coding gene Chr9:75020272-75047834 (-)
C3H/HeJ ENSMUSG00175010936
 protein coding gene Chr9:75052714-75080272 (-)
C57BL/6NJ ENSMUSG00215010623
 protein coding gene Chr9:74949009-74976574 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032459
 protein coding gene Chr9:75043093-75070892 (-)
CAST/EiJ ENSTCUG00005009080
 protein coding gene Chr9:74701621-74729025 (-)
CBA/J ENSMUSG00210013162
 protein coding gene Chr9:75105709-75133268 (-)
DBA/2J ENSMUSG00185007112
 protein coding gene Chr9:75140421-75167979 (-)
FVB/NJ ENSMUSG00205017376
 protein coding gene Chr9:75408872-75436435 (-)
JF1/MsJ ENSUMUG00000019576
 protein coding gene Chr9:75094237-75121744 (-)
LP/J ENSMUSG00230024548
 protein coding gene Chr9:75290892-75318460 (-)
NOD/ShiLtJ ENSMUSG00190024378
 protein coding gene Chr9:75242912-75270475 (-)
NZO/HlLtJ ENSMUSG00225025261
 protein coding gene Chr9:75438357-75465915 (-)
PWK/PhJ ENSLUMG00010015262
 protein coding gene Chr9:75018726-75046329 (-)
SPRET/EiJ ENSMSPG00010003817
 protein coding gene Chr9:76241045-76267842 (-)
WSB/EiJ ENSIUOG00005025400
 protein coding gene Chr9:74564960-74592498 (-)



Homology
more
  • Human Ortholog
    FBXO9, F-box protein 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO9, F-box protein 9
  • Synonyms
    dJ341E18.2, FBX9, NY-REN-57, VCIA1
  • Links
    NCBI Gene ID: 26268
    UniProt: Q9UK97

  • Chr Location
    6p12.1; chr6:53051991-53100873 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    656
  • Tissues
    7
  • cDNA Data
    70
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71538 NCBI Gene Model | MGI Sequence Detail 27567 C57BL/6J ±  kb
    transcript NM_023605 RefSeq | MGI Sequence Detail 2172 C57BL/6  
    polypeptide Q8BK06 UniProt | EBI | MGI Sequence Detail 437 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 72
      cDNA 71
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1889380
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 18
    • Earliest
      J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
    • Latest
      J:380488 Liu L, et al., Ubiquitin ligase subunit FBXO9 inhibits V-ATPase assembly and impedes lung cancer metastasis. Exp Hematol Oncol. 2024 Mar 14;13(1):32
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory