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Osbpl7 Gene Detail
Summary
  • Symbol
    Osbpl7
  • Name
    oxysterol binding protein-like 7
  • Synonyms
    4933437E18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918490
    NCBI Gene: 71240
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96941459-96959730 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 60.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    578 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918490
 protein coding gene Chr11:96941454-96959730 (+)
129S1/SvImJ ENSMUSG00200052572
 protein coding gene Chr11:94188279-94206559 (+)
A/J ENSMUSG00195051854
 protein coding gene Chr11:93914331-93931983 (+)
AKR/J ENSMUSG00220045439
 protein coding gene Chr11:94173456-94191104 (+)
BALB/cJ ENSMUSG00180049445
 protein coding gene Chr11:94170769-94189041 (+)
C3H/HeJ ENSMUSG00175048580
 protein coding gene Chr11:94168350-94186631 (+)
C57BL/6NJ ENSMUSG00215052002
 protein coding gene Chr11:93759162-93777445 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017047
 protein coding gene Chr11:92821839-92840232 (+)
CAST/EiJ ENSTCUG00005047053
 protein coding gene Chr11:93617983-93635590 (+)
CBA/J ENSMUSG00210053203
 protein coding gene Chr11:93876516-93894166 (+)
DBA/2J ENSMUSG00185045304
 protein coding gene Chr11:94218266-94236547 (+)
FVB/NJ ENSMUSG00205047860
 protein coding gene Chr11:94073013-94091288 (+)
JF1/MsJ ENSUMUG00000028329
 protein coding gene Chr11:94529667-94547318 (+)
LP/J ENSMUSG00230049680
 protein coding gene Chr11:95271255-95289532 (+)
NOD/ShiLtJ ENSMUSG00190050525
 protein coding gene Chr11:94264338-94281986 (+)
NZO/HlLtJ ENSMUSG00225052321
 protein coding gene Chr11:97326485-97344765 (+)
PWK/PhJ ENSLUMG00010043432
 protein coding gene Chr11:94072974-94090604 (+)
SPRET/EiJ ENSMSPG00010048492
 protein coding gene Chr11:94571576-94589489 (+)
WSB/EiJ ENSIUOG00005042262
 protein coding gene Chr11:94018816-94037091 (+)



Homology
more
  • Human Ortholog
    OSBPL7, oxysterol binding protein like 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OSBPL7, oxysterol binding protein like 7
  • Synonyms
    ORP7
  • Links
    NCBI Gene ID: 114881
    UniProt: Q9BZF2

  • Chr Location
    17q21.32; chr17:47807367-47821803 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    634
  • Tissues
    28
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71240 NCBI Gene Model | MGI Sequence Detail 18272 C57BL/6J ±  kb
transcript NM_001440151 RefSeq | MGI Sequence Detail 3700 C57BL/6  
polypeptide NP_001427080 RefSeq | MGI Sequence Detail 878 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000648 Oxysterol-binding protein
    IPR018494 Oxysterol-binding protein, conserved site
    IPR037239 Oxysterol-binding protein superfamily
    IPR011993 PH-like domain superfamily
    IPR001849 Pleckstrin homology domain
    IPR041680 Pleckstrin homology domain 8
  • GlyGen
    A2A716 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:354275 Duara J, et al., Oxysterol-binding protein-like 7 deficiency leads to ER stress-mediated apoptosis in podocytes and proteinuria. Am J Physiol Renal Physiol. 2024 Sep 1;327(3):F340-F350
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory