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Arhgap19 Gene Detail
Summary
  • Symbol
    Arhgap19
  • Name
    Rho GTPase activating protein 19
  • Synonyms
    4933411B03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918335
    NCBI Gene: 71085
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:41755027-41790486 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 35.19 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1113 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918335
 protein coding gene Chr19:41755027-41790523 (-)
129S1/SvImJ ENSMUSG00200030135
 protein coding gene Chr19:38487154-38522627 (-)
A/J ENSMUSG00195010585
 protein coding gene Chr19:38590075-38625303 (-)
AKR/J ENSMUSG00220017482
 protein coding gene Chr19:38403922-38439396 (-)
BALB/cJ ENSMUSG00180032487
 protein coding gene Chr19:38842499-38877734 (-)
C3H/HeJ ENSMUSG00175037191
 protein coding gene Chr19:38366145-38401618 (-)
C57BL/6NJ ENSMUSG00215017247
 protein coding gene Chr19:38444491-38479954 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022955
 protein coding gene Chr19:38440284-38476050 (-)
CAST/EiJ ENSTCUG00005015382
 protein coding gene Chr19:38050566-38085910 (-)
CBA/J ENSMUSG00210030338
 protein coding gene Chr19:38448280-38483754 (-)
DBA/2J ENSMUSG00185030680
 protein coding gene Chr19:38968459-39003931 (-)
FVB/NJ ENSMUSG00205007454
 protein coding gene Chr19:37919600-37955078 (-)
JF1/MsJ ENSUMUG00000042872
 protein coding gene Chr19:39135261-39170546 (-)
LP/J ENSMUSG00230029849
 protein coding gene Chr19:39757260-39792732 (-)
NOD/ShiLtJ ENSMUSG00190010895
 protein coding gene Chr19:38318254-38353722 (-)
NZO/HlLtJ ENSMUSG00225042994
 protein coding gene Chr19:43315330-43350803 (-)
PWK/PhJ ENSLUMG00010000876
 protein coding gene Chr19:38301722-38337210 (-)
SPRET/EiJ ENSMSPG00010018815
 protein coding gene Chr19:38033847-38069002 (-)
WSB/EiJ ENSIUOG00005034714
 protein coding gene Chr19:37825491-37860692 (-)



Homology
more
  • Human Ortholog
    ARHGAP19, Rho GTPase activating protein 19
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGAP19, Rho GTPase activating protein 19
  • Synonyms
    CMT2KK
  • Links
    NCBI Gene ID: 84986
    UniProt: Q14CB8

  • Chr Location
    10q24.1; chr10:97222173-97292673 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele are viable with no obvious abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    11
  • cDNA Data
    79
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025154 Ensembl Gene Model | MGI Sequence Detail 35460 C57BL/6J ±  kb
transcript ENSMUST00000026150 Ensembl | MGI Sequence Detail 5103 Not Applicable  
polypeptide ENSMUSP00000026150 Ensembl | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 80
    cDNA 79
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2147478, MGI:2147743
References
more
  • Summaries
    All 48
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory