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Hsfy2 Gene Detail
Summary
  • Symbol
    Hsfy2
  • Name
    heat shock transcription factor, Y-linked 2
  • Synonyms
    4933413G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918316
    NCBI Gene: 71066
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:56675203-56676594 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 28.72 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    109 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918316
 protein coding gene Chr1:56675203-56676610 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016037
 protein coding gene Chr1:56424127-56425518 (-)
A/J MGP_AJ_G0016020
 protein coding gene Chr1:54461267-54462658 (-)
AKR/J MGP_AKRJ_G0015976
 protein coding gene Chr1:55910138-55911529 (-)
BALB/cJ MGP_BALBcJ_G0015975
 protein coding gene Chr1:54499344-54500735 (-)
C3H/HeJ MGP_C3HHeJ_G0015807
 protein coding gene Chr1:56191013-56192404 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016428
 protein coding gene Chr1:58755398-58756789 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014149
 protein coding gene Chr1:50451235-50452627 (-)
CAST/EiJ MGP_CASTEiJ_G0015389
 protein coding gene Chr1:55451258-55452649 (-)
CBA/J MGP_CBAJ_G0015779
 protein coding gene Chr1:60444484-60445875 (-)
DBA/2J MGP_DBA2J_G0015880
 protein coding gene Chr1:53877080-53878471 (-)
FVB/NJ MGP_FVBNJ_G0015882
 protein coding gene Chr1:53204614-53206005 (-)
LP/J MGP_LPJ_G0015952
 protein coding gene Chr1:57297156-57298547 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015902
 protein coding gene Chr1:63514972-63516363 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016475
 protein coding gene Chr1:55902357-55903748 (-)
PWK/PhJ MGP_PWKPhJ_G0015175
 protein coding gene Chr1:53208486-53209878 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014956
 protein coding gene Chr1:55490383-55491774 (-)
WSB/EiJ MGP_WSBEiJ_G0015452
 protein coding gene Chr1:55570147-55571538 (-)



Homology
more
  • Human Ortholog
    HSFY1, heat shock transcription factor Y-linked 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HSFY1, heat shock transcription factor Y-linked 1
  • Synonyms
    HSF2L, HSFY
  • Links
    NCBI Gene ID: 86614
    UniProt: Q96LI6

  • Chr Location
    Yq11.222; chrY:18529643-18588963 (+)  GRCh38
  • Human Ortholog
    HSFY2, heat shock transcription factor Y-linked 2
  • Synonyms
    HSF2L, HSFY
  • Links
    NCBI Gene ID: 159119
    UniProt: Q96LI6

  • Chr Location
    Yq11.222
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    10
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000045336 Ensembl Gene Model | MGI Sequence Detail 1392 C57BL/6J ±  kb
    transcript ENSMUST00000062085 Ensembl | MGI Sequence Detail 1392 Not Applicable  
    polypeptide ENSMUSP00000049715 Ensembl | MGI Sequence Detail 392 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR000232 Heat shock factor (HSF)-type, DNA-binding
      IPR036390 Winged helix DNA-binding domain superfamily
      IPR036388 Winged helix-like DNA-binding domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 2
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 2
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:347775 Yoshimura S, et al., Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions. Nat Commun. 2024 Apr 29;15(1):3330
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/16/2026
    MGI 6.24     		The Jackson Laboratory