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Alyreffm1 Gene Detail
Summary
  • Symbol
    Alyreffm1
  • Name
    Aly/REF export factor family member 1
  • Synonyms
    4930563O14Rik, 4931428L18Rik
Location &
Maps
more
  • Sequence Map
    Chr1:31180159-31261737 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 11.52 cM, cytoband A5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2474 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918238
protein coding gene Chr1:31036933-31261765 (-)
129S1/SvImJ ENSMUSG00200000780
protein coding gene Chr1:28536475-28600780 (-)
129S1/SvImJ ENSMUSG00200000791
protein coding gene Chr1:28549048-28765005 (-)
A/J ENSMUSG00195000055
protein coding gene Chr1:28276394-28480228 (-)
A/J ENSMUSG00195000054
protein coding gene Chr1:28255293-28319537 (-)
AKR/J ENSMUSG00220000531
protein coding gene Chr1:28263343-28480325 (-)
AKR/J ENSMUSG00220000527
protein coding gene Chr1:28250805-28313920 (-)
BALB/cJ ENSMUSG00180001100
protein coding gene Chr1:28346708-28409822 (-)
BALB/cJ ENSMUSG00180001101
protein coding gene Chr1:28359247-28574068 (-)
C3H/HeJ ENSMUSG00175000644
protein coding gene Chr1:28299727-28480197 (-)
C3H/HeJ ENSMUSG00175000643
protein coding gene Chr1:28255293-28319537 (-)
C57BL/6NJ ENSMUSG00215001030
protein coding gene Chr1:28359491-28563301 (-)
C57BL/6NJ ENSMUSG00215001029
protein coding gene Chr1:28338353-28402641 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014007
protein coding gene Chr1:26166431-26250807 (-)
CAST/EiJ ENSTCUG00005000346
protein coding gene Chr1:28385910-28448751 (-)
CBA/J ENSMUSG00210010576
protein coding gene Chr1:28114861-28179100 (-)
CBA/J ENSMUSG00210010584
protein coding gene Chr1:28137848-28339779 (-)
DBA/2J ENSMUSG00185016397
protein coding gene Chr1:29298684-29405481 (-)
DBA/2J ENSMUSG00185016392
protein coding gene Chr1:29174549-29238793 (-)
FVB/NJ ENSMUSG00205006648
protein coding gene Chr1:28268198-28494355 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230000378
protein coding gene Chr1:29206861-29271170 (-)
LP/J ENSMUSG00230000382
protein coding gene Chr1:29251346-29435383 (-)
NOD/ShiLtJ ENSMUSG00190000055
protein coding gene Chr1:28274405-28476343 (-)
NOD/ShiLtJ ENSMUSG00190000054
protein coding gene Chr1:28251418-28315663 (-)
NZO/HlLtJ ENSMUSG00225013913
protein coding gene Chr1:32479801-32544068 (-)
NZO/HlLtJ ENSMUSG00225013929
protein coding gene Chr1:32492360-32708298 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005001827
protein coding gene Chr1:28240689-28303874 (-)



Homology
more
  • Human Ortholog
    ALYREF, Aly/REF export factor
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALYREF, Aly/REF export factor
  • Synonyms
    ALY, ALY/REF, BEF, REF, THOC4
  • Links
    NCBI Gene ID: 10189
    UniProt: Q86V81

  • Chr Location
    17q25.3; chr17:81887835-81891587 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 70988 NCBI Gene Model | MGI Sequence Detail 81579 C57BL/6J ±  kb
transcript NR_033445 RefSeq | MGI Sequence Detail 1094 C57BL/6  
polypeptide A0A087WNP0 UniProt | EBI | MGI Sequence Detail 241 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR051229 ALYREF mRNA export adapter
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR025715 RNA annealing protein YRA2, C-terminal
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
  • GlyGen
    A0A087WNP0 1 site
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
Other
Accession IDs
less
MGI:1922507, MGI:7595543
References
more
  • Summaries
    All 25
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory