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Efcab3 Gene Detail
Summary
  • Symbol
    Efcab3
  • Name
    EF-hand calcium binding domain 3
  • Synonyms
    4921510J17Rik, Efcab15, Gm11639
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918144
    NCBI Gene: 70894
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:104576533-105008363 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, Syntenic
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    11500 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918144
 protein coding gene Chr11:104576533-105008365 (+)
129S1/SvImJ ENSMUSG00200032491
 protein coding gene Chr11:102269859-102320092 (+)
129S1/SvImJ ENSMUSGG00200054664
 protein coding gene Chr11:101873784-101940518 (+)
A/J ENSMUSG00195048625
 protein coding gene Chr11:101961258-102011560 (+)
A/J ENSMUSGG00195055527
 protein coding gene Chr11:101563050-101629798 (+)
AKR/J ENSMUSGG00220054943
 protein coding gene Chr11:101794736-101861471 (+)
AKR/J ENSMUSG00220048602
 protein coding gene Chr11:102187703-102237952 (+)
BALB/cJ ENSMUSGG00180055303
 protein coding gene Chr11:101893176-101966754 (+)
BALB/cJ ENSMUSG00180015740
 protein coding gene Chr11:102285367-102335616 (+)
C3H/HeJ ENSMUSGG00175054844
 protein coding gene Chr11:101847398-101914142 (+)
C3H/HeJ ENSMUSG00175012576
 protein coding gene Chr11:102240330-102290561 (+)
C57BL/6NJ ENSMUSG00215052553
 protein coding gene Chr11:101789611-101839849 (+)
C57BL/6NJ ENSMUSGG00215055828
 protein coding gene Chr11:101409631-101476052 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017297
 protein coding gene Chr11:100867476-101055177 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210055134
 protein coding gene Chr11:101538836-101605595 (+)
CBA/J ENSMUSG00210051930
 protein coding gene Chr11:101942950-101993183 (+)
DBA/2J ENSMUSG00185018806
 protein coding gene Chr11:102290131-102340364 (+)
DBA/2J ENSMUSGG00185057612
 protein coding gene Chr11:101897203-101963944 (+)
FVB/NJ ENSMUSGG00205054705
 protein coding gene Chr11:101707261-101780860 (+)
FVB/NJ ENSMUSG00205036147
 protein coding gene Chr11:102099259-102149489 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230034386
 protein coding gene Chr11:103342382-103392612 (+)
LP/J ENSMUSGG00230055546
 protein coding gene Chr11:102949485-103016206 (+)
NOD/ShiLtJ ENSMUSG00190021628
 protein coding gene Chr11:102293141-102343376 (+)
NOD/ShiLtJ ENSMUSGG00190054765
 protein coding gene Chr11:101901211-101974773 (+)
NZO/HlLtJ ENSMUSG00225050627
 protein coding gene Chr11:105363113-105413386 (+)
NZO/HlLtJ ENSMUSGG00225055223
 protein coding gene Chr11:104975077-105049176 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    EFCAB3, EF-hand calcium binding domain 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EFCAB3, EF-hand calcium binding domain 3
  • Links
    NCBI Gene ID: 146779
    UniProt: Q8N7B9

  • Chr Location
    17q23.2; chr17:62343941-62416480 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020690 Ensembl Gene Model | MGI Sequence Detail 431831 C57BL/6J ±  kb
    transcript ENSMUST00000212287 Ensembl | MGI Sequence Detail 17848 Not Applicable  
    polypeptide ENSMUSP00000148433 Ensembl | MGI Sequence Detail 5869 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3651790, MGI:5816263, MGI:5897169
    References
    more
    • Summaries
      All 33
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory