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Ccdc81 Gene Detail
Summary
  • Symbol
    Ccdc81
  • Name
    coiled-coil domain containing 81
  • Synonyms
    4921513D09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918134
    NCBI Gene: 70884
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:89515356-89552837 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 50.38 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1020 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918134
 protein coding gene Chr7:89515356-89552837 (-)
129S1/SvImJ ENSMUSG00200026243
 protein coding gene Chr7:76278229-76315682 (-)
A/J ENSMUSG00195039769
 protein coding gene Chr7:80802459-80839921 (-)
AKR/J ENSMUSG00220040054
 protein coding gene Chr7:74272739-74310189 (-)
BALB/cJ ENSMUSG00180034567
 protein coding gene Chr7:77479410-77516858 (-)
C3H/HeJ ENSMUSG00175030868
 protein coding gene Chr7:78166663-78204148 (-)
C57BL/6NJ ENSMUSG00215023001
 protein coding gene Chr7:77350972-77388461 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029977
 protein coding gene Chr7:92939938-92980360 (-)
CAST/EiJ ENSTCUG00005028409
 protein coding gene Chr7:80785899-80823989 (-)
CBA/J ENSMUSG00210034038
 protein coding gene Chr7:78008614-78046094 (-)
DBA/2J ENSMUSG00185031418
 protein coding gene Chr7:82338190-82375672 (-)
FVB/NJ ENSMUSG00205025585
 protein coding gene Chr7:77953670-77991128 (-)
JF1/MsJ ENSUMUG00000008432
 protein coding gene Chr7:87275176-87314538 (-)
LP/J ENSMUSG00230013335
 protein coding gene Chr7:88427741-88465219 (-)
NOD/ShiLtJ ENSMUSG00190027374
 protein coding gene Chr7:78223483-78260914 (-)
NZO/HlLtJ ENSMUSG00225010812
 protein coding gene Chr7:86702440-86739923 (-)
PWK/PhJ ENSLUMG00010033863
 protein coding gene Chr7:76462357-76518385 (-)
SPRET/EiJ ENSMSPG00010011652
 protein coding gene Chr7:77527071-77561533 (-)
WSB/EiJ ENSIUOG00005033348
 protein coding gene Chr7:78597536-78635018 (-)



Homology
more
  • Human Ortholog
    CCDC81, coiled-coil domain containing 81
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC81, coiled-coil domain containing 81
  • Links
    NCBI Gene ID: 60494
    UniProt: Q6ZN84

  • Chr Location
    11q14.2; chr11:86374736-86423109 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    33 phenotype references
Male mice homozygous for a knock-out allele are fertile and exhibit normal testis gross appearance, normal testis and epididymis histology and germ cell number, and normal sperm morphology and motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    3
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70884 NCBI Gene Model | MGI Sequence Detail 37482 C57BL/6J ±  kb
transcript NM_001162979 RefSeq | MGI Sequence Detail 2691 ZRU/MplStud  
polypeptide Q9D5W4 UniProt | EBI | MGI Sequence Detail 654 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000032314 coiled-coil domain-containing protein 81
    (term hierarchy)
  • InterPro Domains
    IPR028034 CCDC81, HU domain 1
    IPR040673 CCDC81, HU domain 2
    IPR026295 Coiled-coil domain-containing protein 81
    IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily
  • GlyGen
    Q9D5W4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 59
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 33
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:385753 Qiu Y, et al., CRISPR/Cas9-mediated Genome-editing Reveals 10 Testis-enriched Genes and One Non-testis-enriched Gene are Dispensable for Male Fecundity in Mice. Andrology. 2025 Nov 10;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory