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Spata16 Gene Detail
Summary
  • Symbol
    Spata16
  • Name
    spermatogenesis associated 16
  • Synonyms
    4921511F01Rik, 4930503K02Rik, Nyd-sp12, spermatogenesis-related protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918112
    NCBI Gene: 70862
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:26691769-27037361 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 10.74 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8475 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918112
 protein coding gene Chr3:26691769-27037398 (+)
129S1/SvImJ ENSMUSG00200024245
 protein coding gene Chr3:23413106-23759782 (+)
A/J ENSMUSG00195020505
 protein coding gene Chr3:23536670-23888631 (+)
AKR/J ENSMUSG00220008356
 protein coding gene Chr3:23533604-23887147 (+)
BALB/cJ ENSMUSG00180030591
 protein coding gene Chr3:23523034-23868613 (+)
C3H/HeJ ENSMUSG00175025314
 protein coding gene Chr3:23527746-23879703 (+)
C57BL/6NJ ENSMUSG00215014983
 protein coding gene Chr3:23787220-24132833 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024886
 protein coding gene Chr3:21839583-22145771 (+)
CAST/EiJ ENSTCUG00005024633
 protein coding gene Chr3:23360979-23714997 (+)
CBA/J ENSMUSG00210033568
 protein coding gene Chr3:23509486-23865564 (+)
DBA/2J ENSMUSG00185009305
 protein coding gene Chr3:23752475-24099124 (+)
FVB/NJ ENSMUSG00205008365
 protein coding gene Chr3:23079822-23421014 (+)
JF1/MsJ ENSUMUG00000003923
 protein coding gene Chr3:23271509-23580796 (+)
LP/J ENSMUSG00230001634
 protein coding gene Chr3:25642685-25991646 (+)
NOD/ShiLtJ ENSMUSG00190031783
 protein coding gene Chr3:23805837-24158390 (+)
NZO/HlLtJ ENSMUSG00225006992
 protein coding gene Chr3:28264089-28626597 (+)
PWK/PhJ ENSLUMG00010031966
 protein coding gene Chr3:23233244-23556334 (+)
SPRET/EiJ ENSMSPG00010024238
 protein coding gene Chr3:23577939-23928499 (+)
WSB/EiJ ENSIUOG00005033745
 protein coding gene Chr3:23789156-24128287 (+)



Homology
more
  • Human Ortholog
    SPATA16, spermatogenesis associated 16
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA16, spermatogenesis associated 16
  • Synonyms
    NYD-SP12, SPGF6
  • Links
    NCBI Gene ID: 83893
    UniProt: Q9BXB7

  • Chr Location
    3q26.31; chr3:172889357-173141235 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Spata16 mouse models; 1 with human SPATA16 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a deletion of the fourth exon exhibit male infertility mice due to spermiogenic arrest but not globozoospermia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    9
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039335 Ensembl Gene Model | MGI Sequence Detail 345593 C57BL/6J ±  kb
    transcript ENSMUST00000047005 Ensembl | MGI Sequence Detail 2022 Not Applicable  
    polypeptide ENSMUSP00000043378 Ensembl | MGI Sequence Detail 571 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1922288
    References
    more
    • Summaries
      All 35
      Diseases 2
      Gene Ontology 9
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory