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Pwwp2a Gene Detail
Summary
  • Symbol
    Pwwp2a
  • Name
    PWWP domain containing 2A
  • Synonyms
    4631424J17Rik, D930040F23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918052
    NCBI Gene: 70802
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:43572825-43612318 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 25.81 cM, cytoband B1.1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    789 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918052
 protein coding gene Chr11:43566881-43613248 (+)
129S1/SvImJ ENSMUSG00200006983
 protein coding gene Chr11:40645684-40684103 (+)
A/J ENSMUSG00195006871
 protein coding gene Chr11:40598028-40636451 (+)
AKR/J ENSMUSG00220003238
 protein coding gene Chr11:40796937-40835362 (+)
BALB/cJ ENSMUSG00180001722
 protein coding gene Chr11:40590085-40628508 (+)
C3H/HeJ ENSMUSG00175003601
 protein coding gene Chr11:40591605-40630024 (+)
C57BL/6NJ ENSMUSG00215008207
 protein coding gene Chr11:40512360-40550782 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016227
 protein coding gene Chr11:38897023-38937020 (+)
CAST/EiJ ENSTCUG00005012903
 protein coding gene Chr11:40320082-40359101 (+)
CBA/J ENSMUSG00210006433
 protein coding gene Chr11:40480830-40519249 (+)
DBA/2J ENSMUSG00185009957
 protein coding gene Chr11:40668298-40706722 (+)
FVB/NJ ENSMUSG00205011347
 protein coding gene Chr11:40600257-40638687 (+)
JF1/MsJ ENSUMUG00000019187
 protein coding gene Chr11:40880288-40918999 (+)
LP/J ENSMUSG00230028244
 protein coding gene Chr11:41809991-41848407 (+)
NOD/ShiLtJ ENSMUSG00190007246
 protein coding gene Chr11:40698691-40737105 (+)
NZO/HlLtJ ENSMUSG00225034861
 protein coding gene Chr11:43762406-43800833 (+)
PWK/PhJ ENSLUMG00010007152
 protein coding gene Chr11:40471690-40510382 (+)
SPRET/EiJ ENSMSPG00010002176
 protein coding gene Chr11:41055585-41094493 (+)
WSB/EiJ ENSIUOG00005002027
 protein coding gene Chr11:40456475-40495521 (+)



Homology
more
  • Human Ortholog
    PWWP2A, PWWP domain containing 2A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PWWP2A, PWWP domain containing 2A
  • Synonyms
    MST101
  • Links
    NCBI Gene ID: 114825
    UniProt: Q96N64

  • Chr Location
    5q33.3; chr5:160044316-160119478 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    17
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044950 Ensembl Gene Model | MGI Sequence Detail 39494 C57BL/6J ±  kb
transcript ENSMUST00000061070 Ensembl | MGI Sequence Detail 3277 Not Applicable  
polypeptide ENSMUSP00000054154 Ensembl | MGI Sequence Detail 730 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144328, MGI:2144418, MGI:2442957
References
more
  • Summaries
    All 44
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory