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Abhd17b Gene Detail
Summary
  • Symbol
    Abhd17b
  • Name
    abhydrolase domain containing 17B
  • Synonyms
    5730446C15Rik, Fam108b, MGC:40949
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917816
    NCBI Gene: 226016
  • Alliance
    genome feature page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:21630549-21663001 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 15.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    927 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917816
 protein coding gene Chr19:21630483-21663002 (+)
129S1/SvImJ ENSMUSG00200020225
 protein coding gene Chr19:18387531-18419988 (+)
A/J ENSMUSG00195016303
 protein coding gene Chr19:18509534-18542012 (+)
AKR/J ENSMUSG00220010304
 protein coding gene Chr19:18483304-18515781 (+)
BALB/cJ ENSMUSG00180018316
 protein coding gene Chr19:18856344-18888827 (+)
C3H/HeJ ENSMUSG00175003315
 protein coding gene Chr19:18212888-18245368 (+)
C57BL/6NJ ENSMUSG00215017091
 protein coding gene Chr19:18239761-18272221 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022817
 protein coding gene Chr19:18858710-18889362 (+)
CAST/EiJ ENSTCUG00005008446
 protein coding gene Chr19:18111999-18144585 (+)
CBA/J ENSMUSG00210012763
 protein coding gene Chr19:18453090-18485552 (+)
DBA/2J ENSMUSG00185013205
 protein coding gene Chr19:18839247-18871729 (+)
FVB/NJ ENSMUSG00205003285
 protein coding gene Chr19:18264912-18297400 (+)
JF1/MsJ ENSUMUG00000034679
 protein coding gene Chr19:19076835-19109370 (+)
LP/J ENSMUSG00230016620
 protein coding gene Chr19:19698094-19730544 (+)
NOD/ShiLtJ ENSMUSG00190018336
 protein coding gene Chr19:18226201-18258677 (+)
NZO/HlLtJ ENSMUSG00225033609
 protein coding gene Chr19:23445080-23479609 (+)
PWK/PhJ ENSLUMG00010008213
 protein coding gene Chr19:18395024-18427470 (+)
SPRET/EiJ ENSMSPG00010018235
 protein coding gene Chr19:18414044-18446187 (+)
WSB/EiJ ENSIUOG00005006832
 protein coding gene Chr19:17949161-17981628 (+)



Homology
more
  • Human Ortholog
    ABHD17B, abhydrolase domain containing 17B, depalmitoylase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABHD17B, abhydrolase domain containing 17B, depalmitoylase
  • Synonyms
    C9orf77, CGI-67, FAM108B1
  • Links
    NCBI Gene ID: 51104
    UniProt: Q5VST6

  • Chr Location
    9q21.13; chr9:71862452-71911224 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    41
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047368 Ensembl Gene Model | MGI Sequence Detail 32453 C57BL/6J ±  kb
    transcript ENSMUST00000052556 Ensembl | MGI Sequence Detail 2259 Not Applicable  
    polypeptide ENSMUSP00000056099 Ensembl | MGI Sequence Detail 288 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 42
      cDNA 42

      Microarray probesets 4
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 1
      Gene Ontology 10
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:367686 Briere A, et al., Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies. Invest Ophthalmol Vis Sci. 2025 May 1;66(5):7
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory