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Cd248 Gene Detail
Summary
  • Symbol
    Cd248
  • Name
    CD248 antigen, endosialin
  • Synonyms
    2610111G01Rik, Cd164l1, Tem1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917695
    NCBI Gene: 70445
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5118106-5120668 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.24 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917695
 protein coding gene Chr19:5118106-5120710 (+)
129S1/SvImJ ENSMUSG00200043145
 protein coding gene Chr19:1878475-1881079 (+)
A/J ENSMUSG00195052520
 protein coding gene Chr19:2273949-2276553 (+)
AKR/J ENSMUSG00220047328
 protein coding gene Chr19:2047033-2049637 (+)
BALB/cJ ENSMUSG00180049131
 protein coding gene Chr19:2648674-2651278 (+)
C3H/HeJ ENSMUSG00175009505
 protein coding gene Chr19:1893393-1895997 (+)
C57BL/6NJ ENSMUSG00215037778
 protein coding gene Chr19:2116651-2119255 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022532
 protein coding gene Chr19:1821868-1824428 (+)
CAST/EiJ ENSTCUG00005027693
 protein coding gene Chr19:2037264-2039868 (+)
CBA/J ENSMUSG00210044138
 protein coding gene Chr19:1897302-1899906 (+)
DBA/2J ENSMUSG00185038626
 protein coding gene Chr19:2273769-2276373 (+)
FVB/NJ ENSMUSG00205045789
 protein coding gene Chr19:2277044-2279648 (+)
JF1/MsJ ENSUMUG00000049921
 protein coding gene Chr19:2257138-2259742 (+)
LP/J ENSMUSG00230052289
 protein coding gene Chr19:3185419-3188023 (+)
NOD/ShiLtJ ENSMUSG00190049025
 protein coding gene Chr19:1808442-1811046 (+)
NZO/HlLtJ ENSMUSG00225025832
 protein coding gene Chr19:6894166-6896770 (+)
PWK/PhJ ENSLUMG00010007276
 protein coding gene Chr19:2029854-2032458 (+)
SPRET/EiJ ENSMSPG00010045457
 protein coding gene Chr19:2020891-2023495 (+)
WSB/EiJ ENSIUOG00005040033
 protein coding gene Chr19:1908487-1911088 (+)



Homology
more
  • Human Ortholog
    CD248, CD248 molecule
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD248, CD248 molecule
  • Synonyms
    CD164L1, TEM1
  • Links
    NCBI Gene ID: 57124
    UniProt: Q9HCU0

  • Chr Location
    11q13.2; chr11:66314494-66317044 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 3 alleles in 3 genetic backgrounds
    29 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice display decreased growth of implanted abdominal and intestinal tumors, but have normal wound healing and no gross morphological abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1022
  • Tissues
    176
  • cDNA Data
    27
  • Literature Summary
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70445 NCBI Gene Model | MGI Sequence Detail 2563 C57BL/6J ±  kb
    transcript NM_054042 RefSeq | MGI Sequence Detail 2660 Not Specified  
    polypeptide Q91V98 UniProt | EBI | MGI Sequence Detail 765 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 28
      cDNA 27
      Primer pair 1
      Antibodies 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2147605
    References
    more
    • Summaries
      All 71
      Developmental Gene Expression 13
      Gene Ontology 7
      Phenotypes 29
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:367385 Higaki K, et al., Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells. Cell Rep. 2025 Apr 30;44(5):115620
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory