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Fam135b Gene Detail
Summary
  • Symbol
    Fam135b
  • Name
    family with sequence similarity 135, member B
  • Synonyms
    1700010C24Rik, A830008O07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917613
    NCBI Gene: 70363
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:71310800-71600282 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 32.19 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8107 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917613
 protein coding gene Chr15:71303458-71600282 (-)
129S1/SvImJ ENSMUSG00200019501
 protein coding gene Chr15:68382546-68677808 (-)
A/J ENSMUSG00195027127
 protein coding gene Chr15:68453763-68753431 (-)
AKR/J ENSMUSG00220020559
 protein coding gene Chr15:68341717-68655526 (-)
BALB/cJ ENSMUSG00180021162
 protein coding gene Chr15:68243407-68532681 (-)
C3H/HeJ ENSMUSG00175004770
 protein coding gene Chr15:68593779-68883079 (-)
C57BL/6NJ ENSMUSG00215004920
 protein coding gene Chr15:68300063-68597201 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019856
 protein coding gene Chr15:65050618-65234167 (-)
CAST/EiJ ENSTCUG00005019577
 protein coding gene Chr15:67958120-68241437 (-)
CBA/J ENSMUSG00210024913
 protein coding gene Chr15:68375734-68664991 (-)
DBA/2J ENSMUSG00185024985
 protein coding gene Chr15:68323235-68619377 (-)
FVB/NJ ENSMUSG00205009614
 protein coding gene Chr15:68063834-68347940 (-)
JF1/MsJ ENSUMUG00000017466
 protein coding gene Chr15:68011230-68272731 (-)
LP/J ENSMUSG00230023998
 protein coding gene Chr15:71667187-71976416 (-)
NOD/ShiLtJ ENSMUSG00190004368
 protein coding gene Chr15:68422457-68718394 (-)
NZO/HlLtJ ENSMUSG00225052388
 protein coding gene Chr15:71971176-72267374 (-)
PWK/PhJ ENSLUMG00010010767
 protein coding gene Chr15:68298070-68569576 (-)
SPRET/EiJ ENSMSPG00010004011
 protein coding gene Chr15:69921615-70203794 (-)
WSB/EiJ ENSIUOG00005019741
 protein coding gene Chr15:68408034-68704265 (-)



Homology
more
  • Human Ortholog
    FAM135B, family with sequence similarity 135 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM135B, family with sequence similarity 135 member B
  • Synonyms
    C8ORFK32
  • Links
    NCBI Gene ID: 51059
    UniProt: Q49AJ0

  • Chr Location
    8q24.23; chr8:138130023-138497730 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    3
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70363 NCBI Gene Model | MGI Sequence Detail 289483 C57BL/6J ±  kb
transcript NM_177819 RefSeq | MGI Sequence Detail 4623 C57BL/6  
polypeptide Q9DAI6 UniProt | EBI | MGI Sequence Detail 1403 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 7
Other
Accession IDs
less
MGI:3618858
References
more
  • Summaries
    All 52
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 32
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory