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Pigw Gene Detail
Summary
  • Symbol
    Pigw
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class W
  • Synonyms
    2610044A17Rik, Gwt1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917575
    NCBI Gene: 70325
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:84767141-84771111 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.34 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    154 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917575
 protein coding gene Chr11:84767139-84771111 (-)
129S1/SvImJ ENSMUSG00200019991
 protein coding gene Chr11:81911962-81915932 (-)
A/J ENSMUSG00195007470
 protein coding gene Chr11:81766493-81770464 (-)
AKR/J ENSMUSG00220011250
 protein coding gene Chr11:81975747-81979930 (-)
BALB/cJ ENSMUSG00180011395
 protein coding gene Chr11:81957799-81961768 (-)
C3H/HeJ ENSMUSG00175029807
 protein coding gene Chr11:81913360-81917330 (-)
C57BL/6NJ ENSMUSG00215028430
 protein coding gene Chr11:81541435-81545406 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016899
 protein coding gene Chr11:80123540-80127405 (-)
CAST/EiJ ENSTCUG00005041477
 protein coding gene Chr11:81476614-81480639 (-)
CBA/J ENSMUSG00210032230
 protein coding gene Chr11:81731015-81734987 (-)
DBA/2J ENSMUSG00185018506
 protein coding gene Chr11:82057309-82061492 (-)
FVB/NJ ENSMUSG00205013588
 protein coding gene Chr11:81845475-81849446 (-)
JF1/MsJ ENSUMUG00000011047
 protein coding gene Chr11:82378608-82382791 (-)
LP/J ENSMUSG00230023642
 protein coding gene Chr11:83081094-83085064 (-)
NOD/ShiLtJ ENSMUSG00190017743
 protein coding gene Chr11:82057610-82061580 (-)
NZO/HlLtJ ENSMUSG00225039394
 protein coding gene Chr11:85186396-85190376 (-)
PWK/PhJ ENSLUMG00010024881
 protein coding gene Chr11:81880163-81884144 (-)
SPRET/EiJ ENSMSPG00010027927
 protein coding gene Chr11:82347474-82351427 (-)
WSB/EiJ ENSIUOG00005007691
 protein coding gene Chr11:81866566-81870550 (-)



Homology
more
  • Human Ortholog
    PIGW, phosphatidylinositol glycan anchor biosynthesis class W
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIGW, phosphatidylinositol glycan anchor biosynthesis class W
  • Synonyms
    Gwt1, HPMRS5
  • Links
    NCBI Gene ID: 284098
    UniProt: Q7Z7B1

  • Chr Location
    17q12; chr17:36534987-36539310 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PIGW associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    691
  • Tissues
    94
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045140 Ensembl Gene Model | MGI Sequence Detail 3971 C57BL/6J ±  kb
transcript ENSMUST00000067058 Ensembl | MGI Sequence Detail 2675 Not Applicable  
polypeptide ENSMUSP00000064547 Ensembl | MGI Sequence Detail 503 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 1
References
more
  • Summaries
    All 46
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 10
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:334297 Warren EB, et al., 17q12 deletion syndrome mouse model shows defects in craniofacial, brain and kidney development, and glucose homeostasis. Dis Model Mech. 2022 Dec 1;15(12):dmm049752
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory