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Krt78 Gene Detail
Summary
  • Symbol
    Krt78
  • Name
    keratin 78
  • Synonyms
    2310030B04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917529
    NCBI Gene: 332131
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101854436-101862722 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    387 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917529
 protein coding gene Chr15:101854436-101905059 (-)
129S1/SvImJ ENSMUSG00200049692
 protein coding gene Chr15:99080126-99088406 (-)
A/J ENSMUSG00195043606
 protein coding gene Chr15:98947904-98956189 (-)
AKR/J ENSMUSG00220044853
 protein coding gene Chr15:98939866-98948152 (-)
BALB/cJ ENSMUSG00180040655
 protein coding gene Chr15:98851948-98860228 (-)
C3H/HeJ ENSMUSG00175044460
 protein coding gene Chr15:99127803-99136089 (-)
C57BL/6NJ ENSMUSG00215047334
 protein coding gene Chr15:98895352-98903636 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020332
 protein coding gene Chr15:95782542-95790566 (-)
CAST/EiJ ENSTCUG00005046211
 protein coding gene Chr15:98370912-98379016 (-)
CBA/J ENSMUSG00210025563
 protein coding gene Chr15:98901020-98909308 (-)
DBA/2J ENSMUSG00185033525
 protein coding gene Chr15:98939802-98948089 (-)
FVB/NJ ENSMUSG00205020339
 protein coding gene Chr15:98644297-98652584 (-)
JF1/MsJ ENSUMUG00000026367
 protein coding gene Chr15:98399806-98408091 (-)
LP/J ENSMUSG00230038587
 protein coding gene Chr15:102301206-102309486 (-)
NOD/ShiLtJ ENSMUSG00190042433
 protein coding gene Chr15:98879105-98887383 (-)
NZO/HlLtJ ENSMUSG00225027380
 protein coding gene Chr15:102481101-102489440 (-)
PWK/PhJ ENSLUMG00010043299
 protein coding gene Chr15:98612717-98621039 (-)
SPRET/EiJ ENSMSPG00010036957
 protein coding gene Chr15:100401604-100409756 (-)
WSB/EiJ ENSIUOG00005031997
 protein coding gene Chr15:99030456-99038606 (-)



Homology
more
  • Human Ortholog
    KRT78, keratin 78
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT78, keratin 78
  • Synonyms
    CK-78, K5B, K78, Kb40
  • Links
    NCBI Gene ID: 196374
    UniProt: Q8N1N4

  • Chr Location
    12q13.13; chr12:52837804-52849092 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050463 Ensembl Gene Model | MGI Sequence Detail 8287 C57BL/6J ±  kb
transcript ENSMUST00000164932 Ensembl | MGI Sequence Detail 3437 Not Applicable  
polypeptide ENSMUSP00000126197 Ensembl | MGI Sequence Detail 1068 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR039008 Intermediate filament, rod domain
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
  • GlyGen
    E9Q0F0 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 52
    Diseases 1
    Gene Ontology 4
    Phenotypes 32
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory