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Ly6g6e Gene Detail
Summary
  • Symbol
    Ly6g6e
  • Name
    lymphocyte antigen 6 family member G6E
  • Synonyms
    2310011I02Rik, G6e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917524
    NCBI Gene: 70274
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35295878-35297780 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 18.59 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917524
 protein coding gene Chr17:35295843-35297781 (+)
129S1/SvImJ ENSMUSG00200048649
 protein coding gene Chr17:31000002-31001904 (+)
A/J ENSMUSG00195039766
 protein coding gene Chr17:31899934-31901833 (+)
AKR/J ENSMUSG00220051678
 protein coding gene Chr17:30928813-30930707 (+)
BALB/cJ ENSMUSG00180035230
 protein coding gene Chr17:31269790-31271689 (+)
C3H/HeJ ENSMUSG00175032598
 protein coding gene Chr17:30814923-30816816 (+)
C57BL/6NJ ENSMUSG00215052100
 protein coding gene Chr17:30840217-30842119 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021500
 protein coding gene Chr17:31818460-31820339 (+)
CAST/EiJ ENSTCUG00005049624
 protein coding gene Chr17:31857613-31859515 (+)
CBA/J ENSMUSG00210036116
 protein coding gene Chr17:30637022-30638916 (+)
DBA/2J ENSMUSG00185045137
 protein coding gene Chr17:33289039-33290938 (+)
FVB/NJ ENSMUSG00205038851
 protein coding gene Chr17:31157489-31159392 (+)
JF1/MsJ ENSUMUG00000057081
 protein coding gene Chr17:32541500-32543414 (+)
LP/J ENSMUSG00230054409
 protein coding gene Chr17:34398250-34400152 (+)
NOD/ShiLtJ ENSMUSG00190031125
 protein coding gene Chr17:30758798-30760700 (+)
NZO/HlLtJ ENSMUSG00225054335
 protein coding gene Chr17:36410438-36412344 (+)
PWK/PhJ ENSLUMG00010038758
 protein coding gene Chr17:30376656-30378572 (+)
SPRET/EiJ ENSMSPG00010038346
 protein coding gene Chr17:31560743-31562396 (+)
WSB/EiJ ENSIUOG00005046480
 protein coding gene Chr17:31485979-31487877 (+)



Homology
more
  • Human Ortholog
    LY6G6E, lymphocyte antigen 6 family member G6E (pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LY6G6E, lymphocyte antigen 6 family member G6E (pseudogene)
  • Synonyms
    C6orf22, G6e, LY6G6EP
  • Links
    NCBI Gene ID: 79136

  • Chr Location
    6p21.33; chr6:31711976-31714065 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    607
  • Tissues
    9
  • cDNA Data
    9
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000013766 Ensembl Gene Model | MGI Sequence Detail 1903 C57BL/6J ±  kb
transcript ENSMUST00000172959 Ensembl | MGI Sequence Detail 501 Not Applicable  
polypeptide ENSMUSP00000133753 Ensembl | MGI Sequence Detail 166 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000472 Activin types I and II receptor domain
    IPR039700 Lymphocyte antigen 6G6e
    IPR045860 Snake toxin-like superfamily
Molecular
Reagents
less
  • All nucleic 12
    cDNA 9
    Primer pair 3

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:367802 Kinman AI, et al., Atypical hippocampal excitatory neurons express and govern object memory. Nat Commun. 2025 Feb 12;16(1):1195
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory