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Pik3ip1 Gene Detail
Summary
  • Symbol
    Pik3ip1
  • Name
    phosphoinositide-3-kinase interacting protein 1
  • Synonyms
    1500004A08Rik, 5830455E04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917016
    NCBI Gene: 216505
  • Alliance
    genome feature page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3280731-3292971 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 2.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    340 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917016
 protein coding gene Chr11:3280401-3292971 (+)
129S1/SvImJ ENSMUSG00200030997
 protein coding gene Chr11:233441-246031 (+)
A/J ENSMUSG00195022718
 protein coding gene Chr11:140718-153332 (+)
AKR/J ENSMUSG00220008289
 protein coding gene Chr11:153866-166438 (+)
BALB/cJ ENSMUSG00180023945
 protein coding gene Chr11:163706-176287 (+)
C3H/HeJ ENSMUSG00175009338
 protein coding gene Chr11:153522-166088 (+)
C57BL/6NJ ENSMUSG00215027755
 protein coding gene Chr11:163832-176406 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016008
 protein coding gene Chr11:160809-173595 (+)
CAST/EiJ ENSTCUG00005035715
 protein coding gene Chr11:248299-260901 (+)
CBA/J ENSMUSG00210017624
 protein coding gene Chr11:153269-165841 (+)
DBA/2J ENSMUSG00185016477
 protein coding gene Chr11:250878-263448 (+)
FVB/NJ ENSMUSG00205028910
 protein coding gene Chr11:124165-136772 (+)
JF1/MsJ ENSUMUG00000042967
 protein coding gene Chr11:396447-409395 (+)
LP/J ENSMUSG00230031525
 protein coding gene Chr11:1316675-1329261 (+)
NOD/ShiLtJ ENSMUSG00190028545
 protein coding gene Chr11:140635-153256 (+)
NZO/HlLtJ ENSMUSG00225025300
 protein coding gene Chr11:3373633-3386198 (+)
PWK/PhJ ENSLUMG00010017689
 protein coding gene Chr11:141611-154416 (+)
SPRET/EiJ ENSMSPG00010008337
 protein coding gene Chr11:225068-240967 (+)
WSB/EiJ ENSIUOG00005007073
 protein coding gene Chr11:154519-167139 (+)



Homology
more
  • Human Ortholog
    PIK3IP1, phosphoinositide-3-kinase interacting protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIK3IP1, phosphoinositide-3-kinase interacting protein 1
  • Synonyms
    HGFL, hHGFL(S), TrIP
  • Links
    NCBI Gene ID: 113791
    UniProt: Q96FE7

  • Chr Location
    22q12.2; chr22:31281593-31292534 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Mice homozygous for an ENU-induced allele exhibit normal blood lymphocyte populations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    704
  • Tissues
    24
  • cDNA Data
    15
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 216505 NCBI Gene Model | MGI Sequence Detail 12241 C57BL/6J ±  kb
transcript NM_178149 RefSeq | MGI Sequence Detail 2267 C57BL/6  
polypeptide Q7TMJ8 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1
    Antibodies 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1923333
References
more
  • Summaries
    All 49
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:377315 Zhang X, et al., IRF4 expression by NK precursors predetermines exhaustion of NK cells during tumor metastasis. Nat Immunol. 2025 Jul;26(7):1062-1073
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory