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Sack1g Gene Detail
Summary
  • Symbol
    Sack1g
  • Name
    scaffolding CK1 anchoring protein G
  • Synonyms
    2310040C09Rik, Fam83g, wly
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916890
    NCBI Gene: 69640
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:61574917-61600777 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 37.96 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    573 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916890
 protein coding gene Chr11:61574908-61600777 (+)
129S1/SvImJ ENSMUSG00200036689
 protein coding gene Chr11:58491858-58517772 (+)
A/J ENSMUSG00195031477
 protein coding gene Chr11:58534240-58560212 (+)
AKR/J ENSMUSG00220047191
 protein coding gene Chr11:58634029-58659963 (+)
BALB/cJ ENSMUSG00180046921
 protein coding gene Chr11:58587353-58613326 (+)
C3H/HeJ ENSMUSG00175035415
 protein coding gene Chr11:58551408-58577376 (+)
C57BL/6NJ ENSMUSG00215028123
 protein coding gene Chr11:58294352-58320321 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016483
 protein coding gene Chr11:56499724-56525596 (+)
CAST/EiJ ENSTCUG00005041322
 protein coding gene Chr11:58077923-58103843 (+)
CBA/J ENSMUSG00210029418
 protein coding gene Chr11:58384444-58410413 (+)
DBA/2J ENSMUSG00185036329
 protein coding gene Chr11:58566612-58592546 (+)
FVB/NJ ENSMUSG00205035734
 protein coding gene Chr11:58456682-58482621 (+)
JF1/MsJ ENSUMUG00000042793
 protein coding gene Chr11:58975804-59001724 (+)
LP/J ENSMUSG00230049220
 protein coding gene Chr11:59713109-59739047 (+)
NOD/ShiLtJ ENSMUSG00190033582
 protein coding gene Chr11:58565645-58591584 (+)
NZO/HlLtJ ENSMUSG00225043036
 protein coding gene Chr11:61856491-61882429 (+)
PWK/PhJ ENSLUMG00010026916
 protein coding gene Chr11:58504302-58530234 (+)
SPRET/EiJ ENSMSPG00010037086
 protein coding gene Chr11:59176709-59202679 (+)
WSB/EiJ ENSIUOG00005035163
 protein coding gene Chr11:58483900-58509838 (+)



Homology
more
  • Human Ortholog
    SACK1G, scaffolding CK1 anchoring protein G
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SACK1G, scaffolding CK1 anchoring protein G
  • Synonyms
    FAM83G, PAWS1
  • Links
    NCBI Gene ID: 644815
    UniProt: A6ND36

  • Chr Location
    17p11.2; chr17:18968789-19006116 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    2 images
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations at this locus result in curly hair.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042377 Ensembl Gene Model | MGI Sequence Detail 25861 C57BL/6J ±  kb
    transcript ENSMUST00000093019 Ensembl | MGI Sequence Detail 4778 Not Applicable  
    polypeptide ENSMUSP00000090697 Ensembl | MGI Sequence Detail 812 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144214, MGI:2668516, MGI:8327522
    References
    more
    • Summaries
      All 37
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory