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Smco1 Gene Detail
Summary
  • Symbol
    Smco1
  • Name
    single-pass membrane protein with coiled-coil domains 1
  • Synonyms
    2310010M20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916826
    NCBI Gene: 69576
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:32090298-32093599 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 22.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    187 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916826
 protein coding gene Chr16:32090286-32093599 (+)
129S1/SvImJ ENSMUSG00200035539
 protein coding gene Chr16:29110759-29114074 (+)
A/J ENSMUSG00195027559
 protein coding gene Chr16:28651459-28654781 (+)
AKR/J ENSMUSG00220030810
 protein coding gene Chr16:28943747-28947076 (+)
BALB/cJ ENSMUSG00180026106
 protein coding gene Chr16:28867313-28870637 (+)
C3H/HeJ ENSMUSG00175036148
 protein coding gene Chr16:29012249-29015571 (+)
C57BL/6NJ ENSMUSG00215014229
 protein coding gene Chr16:28895535-28898848 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020668
 protein coding gene Chr16:29266132-29269605 (+)
CAST/EiJ ENSTCUG00005035403
 protein coding gene Chr16:29281183-29284498 (+)
CBA/J ENSMUSG00210031043
 protein coding gene Chr16:29054236-29057557 (+)
DBA/2J ENSMUSG00185017525
 protein coding gene Chr16:28969717-28973038 (+)
FVB/NJ ENSMUSG00205018288
 protein coding gene Chr16:28982998-28986316 (+)
JF1/MsJ ENSUMUG00000020287
 protein coding gene Chr16:29148251-29151531 (+)
LP/J ENSMUSG00230028409
 protein coding gene Chr16:31538491-31541812 (+)
NOD/ShiLtJ ENSMUSG00190028726
 protein coding gene Chr16:29159138-29162453 (+)
NZO/HlLtJ ENSMUSG00225039305
 protein coding gene Chr16:34771566-34774881 (+)
PWK/PhJ ENSLUMG00010028595
 protein coding gene Chr16:28966905-28970257 (+)
SPRET/EiJ ENSMSPG00010018010
 protein coding gene Chr16:28961739-28964812 (+)
WSB/EiJ ENSIUOG00005031625
 protein coding gene Chr16:29137239-29140547 (+)



Homology
more
  • Human Ortholog
    SMCO1, single-pass membrane protein with coiled-coil domains 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMCO1, single-pass membrane protein with coiled-coil domains 1
  • Synonyms
    C3orf43
  • Links
    NCBI Gene ID: 255798
    UniProt: Q147U7

  • Chr Location
    3q29; chr3:196506878-196520955 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69576 NCBI Gene Model | MGI Sequence Detail 3302 C57BL/6J ±  kb
transcript NM_183283 RefSeq | MGI Sequence Detail 1398 C57BL/6  
polypeptide Q8CEZ1 UniProt | EBI | MGI Sequence Detail 214 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000059781 single-pass membrane and coiled-coil domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR027875 Protein of unknown function DUF4547
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:327759 Pollak RM, et al., Metabolic effects of the schizophrenia-associated 3q29 deletion. Transl Psychiatry. 2022 Feb 17;12(1):66
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory