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Fam24b Gene Detail
Summary
  • Symbol
    Fam24b
  • Name
    family with sequence similarity 24 member B
  • Synonyms
    1700007K09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916568
    NCBI Gene: 69318
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:130927673-130931245 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 73.84 cM, cytoband F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916568
 protein coding gene Chr7:130927136-130933163 (-)
129S1/SvImJ ENSMUSG00200024926
 protein coding gene Chr7:117465102-117468678 (-)
A/J ENSMUSG00195040325
 protein coding gene Chr7:121943220-121946796 (-)
AKR/J ENSMUSG00220016262
 protein coding gene Chr7:115403869-115407444 (-)
BALB/cJ ENSMUSG00180011580
 protein coding gene Chr7:118647884-118651457 (-)
C3H/HeJ ENSMUSG00175018035
 protein coding gene Chr7:119374370-119377942 (-)
C57BL/6NJ ENSMUSG00215012984
 protein coding gene Chr7:118643804-118647376 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030565
 protein coding gene Chr7:133516039-133519512 (-)
CAST/EiJ ENSTCUG00005048484
 protein coding gene Chr7:121940286-121943884 (-)
CBA/J ENSMUSG00210023309
 protein coding gene Chr7:119129182-119132755 (-)
DBA/2J ENSMUSG00185022910
 protein coding gene Chr7:123445234-123448806 (-)
FVB/NJ ENSMUSG00205034986
 protein coding gene Chr7:119079743-119083314 (-)
JF1/MsJ ENSUMUG00000045886
 protein coding gene Chr7:128459585-128463140 (-)
LP/J ENSMUSG00230052449
 protein coding gene Chr7:129563619-129567195 (-)
NOD/ShiLtJ ENSMUSG00190014804
 protein coding gene Chr7:119269159-119272731 (-)
NZO/HlLtJ ENSMUSG00225012350
 protein coding gene Chr7:127802725-127806297 (-)
PWK/PhJ ENSLUMG00010038462
 protein coding gene Chr7:117637317-117640866 (-)
SPRET/EiJ ENSMSPG00010010907
 protein coding gene Chr7:118954891-118958374 (-)
WSB/EiJ ENSIUOG00005028392
 protein coding gene Chr7:119974362-119977945 (-)



Homology
more
  • Human Ortholog
    FAM24A, family with sequence similarity 24 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM24A, family with sequence similarity 24 member A
  • Links
    NCBI Gene ID: 118670
    UniProt: A6NFZ4

  • Chr Location
    10q26.13; chr10:122910610-122913111 (+)  GRCh38
  • Human Ortholog
    FAM24B, family with sequence similarity 24 member B
  • Links
    NCBI Gene ID: 196792
    UniProt: Q8N5W8

  • Chr Location
    10q26.13; chr10:122849078-122879641 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal fertility; adult males show no significant changes in relative testis weight, sperm morphology, testis and epididymis histology, or sperm motility parameters.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030858 Ensembl Gene Model | MGI Sequence Detail 3573 C57BL/6J ±  kb
transcript ENSMUST00000188899 Ensembl | MGI Sequence Detail 680 Not Applicable  
polypeptide ENSMUSP00000139545 Ensembl | MGI Sequence Detail 119 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR028122 FAM24 family
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
Other
Accession IDs
less
MGI:6108336
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:385300 Chang HY, et al., Mouse genome engineering uncovers 18 genes dispensable for male reproduction. Andrology. 2026 Mar;14(3):833-846
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory