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Lzic Gene Detail
Summary
  • Symbol
    Lzic
  • Name
    leucine zipper and CTNNBIP1 domain containing
  • Synonyms
    1810030J04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916401
    NCBI Gene: 69151
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:149569686-149581125 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 79.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916401
 protein coding gene Chr4:149569642-149581952 (+)
129S1/SvImJ no annotation
A/J ENSMUSG00195015594
 protein coding gene Chr4:142266883-142269804 (+)
AKR/J no annotation
BALB/cJ ENSMUSG00180044459
 protein coding gene Chr4:139949478-139952399 (+)
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215020301
 protein coding gene Chr4:142073764-142076685 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026817
 protein coding gene Chr4:139352717-139364617 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ ENSMUSG00205031723
 protein coding gene Chr4:140338714-140341757 (+)
JF1/MsJ no annotation
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190003221
 protein coding gene Chr4:141553422-141556480 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LZIC, leucine zipper and CTNNBIP1 domain containing
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LZIC, leucine zipper and CTNNBIP1 domain containing
  • Links
    NCBI Gene ID: 84328
    UniProt: Q8WZA0

  • Chr Location
    1p36.22; chr1:9922113-9943407 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    54
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028990 Ensembl Gene Model | MGI Sequence Detail 11440 C57BL/6J ±  kb
transcript ENSMUST00000030842 Ensembl | MGI Sequence Detail 1817 Not Applicable  
polypeptide ENSMUSP00000030842 Ensembl | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010018 protein LZIC
    (term hierarchy)
  • InterPro Domains
    IPR009428 Beta-catenin-interacting ICAT domain
    IPR036911 Beta-catenin-interacting ICAT superfamily
  • GlyGen
    Q8K3C3 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140544
References
more
  • Summaries
    All 33
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory