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Tmem273 Gene Detail
Summary
  • Symbol
    Tmem273
  • Name
    transmembrane protein 273
  • Synonyms
    1810011H11Rik, 4733401I05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916319
    NCBI Gene: 69069
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:32507920-32539941 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 19.40 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1066 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916319
 protein coding gene Chr14:32507869-32539941 (+)
129S1/SvImJ ENSMUSG00200037615
 protein coding gene Chr14:24330632-24362638 (+)
A/J ENSMUSG00195011822
 protein coding gene Chr14:25405611-25437640 (+)
AKR/J ENSMUSG00220028832
 protein coding gene Chr14:24524393-24556414 (+)
BALB/cJ ENSMUSG00180028676
 protein coding gene Chr14:24494143-24526159 (+)
C3H/HeJ ENSMUSG00175032147
 protein coding gene Chr14:24561324-24593341 (+)
C57BL/6NJ ENSMUSG00215014774
 protein coding gene Chr14:24797983-24830010 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019096
 protein coding gene Chr14:25117833-25147677 (+)
CAST/EiJ ENSTCUG00005023312
 protein coding gene Chr14:24652072-24684276 (+)
CBA/J ENSMUSG00210042282
 protein coding gene Chr14:24804244-24836269 (+)
DBA/2J ENSMUSG00185040275
 protein coding gene Chr14:29073606-29105630 (+)
FVB/NJ ENSMUSG00205015551
 protein coding gene Chr14:24665334-24697338 (+)
JF1/MsJ ENSUMUG00000043089
 protein coding gene Chr14:36333510-36364477 (+)
LP/J ENSMUSG00230032432
 protein coding gene Chr14:36354623-36386639 (+)
NOD/ShiLtJ ENSMUSG00190018162
 protein coding gene Chr14:24817846-24849862 (+)
NZO/HlLtJ ENSMUSG00225036548
 protein coding gene Chr14:30692556-30724571 (+)
PWK/PhJ ENSLUMG00010022454
 protein coding gene Chr14:12936990-12967949 (+)
SPRET/EiJ ENSMSPG00010034781
 protein coding gene Chr14:26505906-26537460 (+)
WSB/EiJ ENSIUOG00005011011
 protein coding gene Chr14:24636228-24668251 (+)



Homology
more
  • Human Ortholog
    TMEM273, transmembrane protein 273
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM273, transmembrane protein 273
  • Synonyms
    C10orf128
  • Links
    NCBI Gene ID: 170371
    UniProt: Q5T292

  • Chr Location
    10q11.23; chr10:49154725-49188585 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041707 Ensembl Gene Model | MGI Sequence Detail 32022 C57BL/6J ±  kb
    transcript ENSMUST00000227871 Ensembl | MGI Sequence Detail 560 Not Applicable  
    polypeptide ENSMUSP00000153805 Ensembl | MGI Sequence Detail 95 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR029395 Protein of unknown function DUF4514
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1918098, MGI:6156535
    References
    more
    • Summaries
      All 26
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory