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Lysmd3 Gene Detail
Summary
  • Symbol
    Lysmd3
  • Name
    LysM, putative peptidoglycan-binding, domain containing 3
  • Synonyms
    1110030H10Rik, MGC:7041
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915906
    NCBI Gene: 80289
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:81805782-81820990 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 43.64 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    503 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915906
 protein coding gene Chr13:81805782-81820990 (+)
129S1/SvImJ ENSMUSG00200005767
 protein coding gene Chr13:76246830-76262038 (+)
A/J ENSMUSG00195024955
 protein coding gene Chr13:76757335-76772543 (+)
AKR/J ENSMUSG00220016401
 protein coding gene Chr13:75303828-75319036 (+)
BALB/cJ ENSMUSG00180001402
 protein coding gene Chr13:77260059-77275266 (+)
C3H/HeJ ENSMUSG00175019026
 protein coding gene Chr13:77505450-77520658 (+)
C57BL/6NJ ENSMUSG00215002502
 protein coding gene Chr13:77385440-77400648 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018744
 protein coding gene Chr13:76018580-76033534 (+)
CAST/EiJ ENSTCUG00005003676
 protein coding gene Chr13:76743658-76757375 (+)
CBA/J ENSMUSG00210005503
 protein coding gene Chr13:76795482-76810690 (+)
DBA/2J ENSMUSG00185016946
 protein coding gene Chr13:80475710-80490918 (+)
FVB/NJ ENSMUSG00205011849
 protein coding gene Chr13:76243538-76258746 (+)
JF1/MsJ ENSUMUG00000023949
 protein coding gene Chr13:80257412-80272614 (+)
LP/J ENSMUSG00230024440
 protein coding gene Chr13:90460885-90476093 (+)
NOD/ShiLtJ ENSMUSG00190008208
 protein coding gene Chr13:76810434-76825642 (+)
NZO/HlLtJ ENSMUSG00225030118
 protein coding gene Chr13:82979326-82994534 (+)
PWK/PhJ ENSLUMG00010014198
 protein coding gene Chr13:76372122-76387325 (+)
SPRET/EiJ ENSMSPG00010001230
 protein coding gene Chr13:77264047-77276842 (+)
WSB/EiJ ENSIUOG00005017351
 protein coding gene Chr13:76093143-76108351 (+)



Homology
more
  • Human Ortholog
    LYSMD3, LysM domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LYSMD3, LysM domain containing 3
  • Links
    NCBI Gene ID: 116068
    UniProt: Q7Z3D4

  • Chr Location
    5q14.3; chr5:90515611-90529596 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    4
  • Genomic Mutations
    1 involving Lysmd3
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    12 strains or lines available
Mice homozygous for a knock-out allele are viable and fertile with normal response to a range of pathogens.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 80289 NCBI Gene Model | MGI Sequence Detail 15209 C57BL/6J ±  kb
transcript NM_030257 RefSeq | MGI Sequence Detail 3139 FVB/N  
polypeptide Q99LE3 UniProt | EBI | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000029617 LysM and putative peptidoglycan-binding domain-containing protein 3
    (term hierarchy)
  • InterPro Domains
    IPR045030 LysM and putative peptidoglycan-binding domain-containing protein 1-4
    IPR018392 LysM domain
    IPR036779 LysM domain superfamily
  • GlyGen
    Q99LE3 4 sites
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:1933110
References
more
  • Summaries
    All 36
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:298059 Mafanda EK, et al., Essential role of suppressor of cytokine signaling 1 (SOCS1) in hepatocytes and macrophages in the regulation of liver fibrosis. Cytokine. 2019 Dec;124:154501
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory