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Vps51 Gene Detail
Summary
  • Symbol
    Vps51
  • Name
    VPS51 GARP complex subunit
  • Synonyms
    1110014N23Rik, 3110057M17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915755
    NCBI Gene: 68505
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:6117872-6127217 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.34 cM, cytoband A
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    275 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915755
 protein coding gene Chr19:6117872-6127261 (-)
129S1/SvImJ ENSMUSG00200048284
 protein coding gene Chr19:2880292-2889681 (-)
A/J ENSMUSG00195046698
 protein coding gene Chr19:3280966-3290383 (-)
AKR/J ENSMUSG00220049212
 protein coding gene Chr19:3054104-3063521 (-)
BALB/cJ ENSMUSG00180039026
 protein coding gene Chr19:3655691-3665112 (-)
C3H/HeJ ENSMUSG00175011155
 protein coding gene Chr19:2905859-2915280 (-)
C57BL/6NJ ENSMUSG00215045044
 protein coding gene Chr19:3118621-3128010 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022589
 protein coding gene Chr19:2854834-2867258 (-)
CAST/EiJ ENSTCUG00005041742
 protein coding gene Chr19:3040089-3049452 (-)
CBA/J ENSMUSG00210037984
 protein coding gene Chr19:2908583-2918000 (-)
DBA/2J ENSMUSG00185044378
 protein coding gene Chr19:3285062-3294479 (-)
FVB/NJ ENSMUSG00205050270
 protein coding gene Chr19:3287219-3296653 (-)
JF1/MsJ ENSUMUG00000012206
 protein coding gene Chr19:3254183-3263520 (-)
LP/J ENSMUSG00230052960
 protein coding gene Chr19:4187175-4196564 (-)
NOD/ShiLtJ ENSMUSG00190021649
 protein coding gene Chr19:2815449-2824866 (-)
NZO/HlLtJ ENSMUSG00225025274
 protein coding gene Chr19:7895987-7905376 (-)
PWK/PhJ ENSLUMG00010004483
 protein coding gene Chr19:3021889-3031228 (-)
SPRET/EiJ ENSMSPG00010046284
 protein coding gene Chr19:3016008-3025262 (-)
WSB/EiJ ENSIUOG00005039340
 protein coding gene Chr19:2928843-2938260 (-)



Homology
more
  • Human Ortholog
    VPS51, VPS51 subunit of GARP complex
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VPS51, VPS51 subunit of GARP complex
  • Synonyms
    ANG2, ANG3, C11orf2, C11orf3, FFR, PCH13
  • Links
    NCBI Gene ID: 738
    UniProt: Q9UID3

  • Chr Location
    11q13.1; chr11:65089324-65111862 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human VPS51 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    8
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    102
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68505 NCBI Gene Model | MGI Sequence Detail 9346 C57BL/6J ±  kb
    transcript NM_001081041 RefSeq | MGI Sequence Detail 2631 Not Specified  
    polypeptide Q3UVL4 UniProt | EBI | MGI Sequence Detail 782 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000007470 vacuolar protein sorting-associated protein 51
      (term hierarchy)
    • InterPro Domains
      IPR016159 Cullin repeat-like-containing domain superfamily
      IPR014812 Vacuolar protein sorting-associated protein 51
    • GlyGen
      Q3UVL4 3 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 103
      Genomic 1
      cDNA 102

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1920440, MGI:2147600
    References
    more
    • Summaries
      All 43
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory