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Card19 Gene Detail
Summary
  • Symbol
    Card19
  • Name
    caspase recruitment domain family, member 19
  • Synonyms
    1110007C09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915730
    NCBI Gene: 68480
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:49356426-49369471 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 25.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    375 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915730
 protein coding gene Chr13:49356426-49369513 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020531
 protein coding gene Chr13:48167772-48180847 (-)
A/J MGP_AJ_G0020485
 protein coding gene Chr13:46455583-46468989 (-)
AKR/J MGP_AKRJ_G0020462
 protein coding gene Chr13:47769022-47782103 (-)
BALB/cJ MGP_BALBcJ_G0020481
 protein coding gene Chr13:46669812-46683818 (-)
C3H/HeJ MGP_C3HHeJ_G0020280
 protein coding gene Chr13:47590057-47603132 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020914
 protein coding gene Chr13:49620319-49635993 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018499
 protein coding gene Chr13:44435274-44448242 (-)
CAST/EiJ MGP_CASTEiJ_G0019795
 protein coding gene Chr13:47595600-47608706 (-)
CBA/J MGP_CBAJ_G0020241
 protein coding gene Chr13:51669544-51682664 (-)
DBA/2J MGP_DBA2J_G0020363
 protein coding gene Chr13:45980728-45993799 (-)
FVB/NJ MGP_FVBNJ_G0020342
 protein coding gene Chr13:45499102-45512297 (-)
LP/J MGP_LPJ_G0020438
 protein coding gene Chr13:48390740-48403819 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020371
 protein coding gene Chr13:51382836-51396986 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020957
 protein coding gene Chr13:47468416-47481980 (-)
PWK/PhJ MGP_PWKPhJ_G0019551
 protein coding gene Chr13:46160818-46174013 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019379
 protein coding gene Chr13:46171274-46184130 (-)
WSB/EiJ MGP_WSBEiJ_G0019857
 protein coding gene Chr13:47781015-47794101 (-)



Homology
more
  • Human Ortholog
    CARD19, caspase recruitment domain family member 19
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CARD19, caspase recruitment domain family member 19
  • Synonyms
    BinCARD, C9orf89
  • Links
    NCBI Gene ID: 84270
    UniProt: Q96LW7

  • Chr Location
    9q22.31; chr9:93096217-93113283 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display enhanced B cell tolerance.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    28
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68480 NCBI Gene Model | MGI Sequence Detail 13046 C57BL/6J ±  kb
transcript NR_184779 RefSeq | MGI Sequence Detail 809 C57BL/6  
polypeptide Q9D1I2 UniProt | EBI | MGI Sequence Detail 183 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 28

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145305
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:365237 Aoto M, et al., The splicing factor Acin1 is essential for embryonic development but has limited effects on muscle structure and homeostasis. Sci Rep. 2025;15(1):14017
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory