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Sycn Gene Detail
Summary
  • Symbol
    Sycn
  • Name
    syncollin
  • Synonyms
    0910001K16Rik, 1810038B08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915666
    NCBI Gene: 68416
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28240310-28241634 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 16.83 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915666
 protein coding gene Chr7:28240310-28241635 (+)
129S1/SvImJ ENSMUSG00200042499
 protein coding gene Chr7:18028650-18029974 (+)
A/J ENSMUSG00195048756
 protein coding gene Chr7:20701918-20703242 (+)
AKR/J ENSMUSG00220047421
 protein coding gene Chr7:23785003-23786327 (-)
BALB/cJ ENSMUSG00180046193
 protein coding gene Chr7:18761478-18762802 (+)
C3H/HeJ ENSMUSG00175047560
 protein coding gene Chr7:19794571-19795895 (+)
C57BL/6NJ ENSMUSG00215053857
 protein coding gene Chr7:17930192-17931516 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029452
 protein coding gene Chr7:27741594-27742930 (+)
CAST/EiJ ENSTCUG00005050350
 protein coding gene Chr7:19728914-19730241 (+)
CBA/J ENSMUSG00210051598
 protein coding gene Chr7:18979164-18980488 (+)
DBA/2J ENSMUSG00185047769
 protein coding gene Chr7:22091856-22093180 (+)
FVB/NJ ENSMUSG00205049196
 protein coding gene Chr7:18767067-18768392 (+)
JF1/MsJ ENSUMUG00000019473
 protein coding gene Chr7:26494895-26496222 (+)
LP/J ENSMUSG00230051783
 protein coding gene Chr7:27262392-27263716 (+)
NOD/ShiLtJ ENSMUSG00190049535
 protein coding gene Chr7:18426142-18427466 (+)
NZO/HlLtJ ENSMUSG00225024451
 protein coding gene Chr7:26105524-26106848 (+)
PWK/PhJ ENSLUMG00010048732
 protein coding gene Chr7:18458943-18460274 (+)
SPRET/EiJ ENSMSPG00010040843
 protein coding gene Chr7:17817097-17818453 (+)
WSB/EiJ ENSIUOG00005053349
 protein coding gene Chr7:12689205-12690533 (+)



Homology
more
  • Human Ortholog
    SYCN, syncollin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYCN, syncollin
  • Synonyms
    INSSA1, SYL
  • Links
    NCBI Gene ID: 342898
    UniProt: Q0VAF6

  • Chr Location
    19q13.2; chr19:39202825-39204263 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice exhibit normal pancreatic morphology, but a reduced rate of pancreatic protein synthesis and intracellular transport of secretory proteins in acinar cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    132
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000084174 Ensembl Gene Model | MGI Sequence Detail 1325 C57BL/6J ±  kb
    transcript ENSMUST00000119180 Ensembl | MGI Sequence Detail 556 Not Applicable  
    polypeptide ENSMUSP00000112770 Ensembl | MGI Sequence Detail 134 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 133
      cDNA 132
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1925561
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:356223 Martinez-Ramirez AS, et al., Specific Temporal Requirement of Prox1 Activity During Pancreatic Acinar Cell Development. Gastro Hep Adv. 2022;1(5):807-823
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory