About   Help   FAQ
Nutf2 Gene Detail
Summary
  • Symbol
    Nutf2
  • Name
    nuclear transport factor 2
  • Synonyms
    2700067I02Rik, Ntf2, PP15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915301
    NCBI Gene: 68051
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:106587212-106605962 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.05 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    483 from dbSNP Build 142
  • Strain Annotations
    25
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915301
 protein coding gene Chr8:106587165-106607034 (+)
129S1/SvImJ ENSMUSG00200013971
 protein coding gene Chr8:100867073-100885824 (+)
A/J ENSMUSG00195008501
 protein coding gene Chr18:7601784-7602654 (-)
A/J ENSMUSG00195016300
 protein coding gene Chr8:101189554-101208305 (+)
AKR/J ENSMUSG00220018623
 protein coding gene Chr18:7592987-7593857 (-)
AKR/J ENSMUSG00220014871
 protein coding gene Chr8:101332191-101350941 (+)
BALB/cJ ENSMUSG00180005317
 protein coding gene Chr18:8041995-8042865 (-)
BALB/cJ ENSMUSG00180021471
 protein coding gene Chr8:101195354-101214107 (+)
C3H/HeJ ENSMUSG00175007240
 protein coding gene Chr18:7577329-7578199 (-)
C3H/HeJ ENSMUSG00175024899
 protein coding gene Chr8:101252066-101270816 (+)
C57BL/6NJ ENSMUSG00215004245
 protein coding gene Chr19:50303802-50304702 (-)
C57BL/6NJ ENSMUSG00215011428
 protein coding gene Chr18:7319274-7320166 (-)
C57BL/6NJ ENSMUSG00215019567
 protein coding gene Chr8:100866413-100885163 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031499
 protein coding gene Chr8:96994466-97014412 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210021531
 protein coding gene Chr18:7590251-7591121 (-)
CBA/J ENSMUSG00210033496
 protein coding gene Chr8:101179785-101198535 (+)
DBA/2J ENSMUSG00185028820
 protein coding gene Chr18:7597581-7598451 (-)
DBA/2J ENSMUSG00185005700
 protein coding gene Chr8:107288543-107307293 (+)
FVB/NJ ENSMUSG00205013582
 protein coding gene Chr8:100164108-100182860 (+)
FVB/NJ ENSMUSG00205028806
 protein coding gene Chr18:7376784-7377654 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230030069
 protein coding gene Chr8:110968949-110987699 (+)
NOD/ShiLtJ ENSMUSG00190025224
 protein coding gene Chr8:101318964-101337714 (+)
NOD/ShiLtJ ENSMUSG00190009427
 protein coding gene Chr18:7370309-7371179 (-)
NZO/HlLtJ ENSMUSG00225021355
 protein coding gene Chr8:114319491-114338240 (+)
NZO/HlLtJ ENSMUSG00225033825
 protein coding gene Chr18:9581022-9581892 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    NUTF2, nuclear transport factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUTF2, nuclear transport factor 2
  • Synonyms
    NTF-2, NTF2, PP15
  • Links
    NCBI Gene ID: 10204
    UniProt: P61970

  • Chr Location
    16q22.1; chr16:67846867-67872569 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    869
  • Tissues
    100
  • cDNA Data
    17
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000008450 Ensembl Gene Model | MGI Sequence Detail 18751 C57BL/6J ±  kb
    transcript ENSMUST00000008594 Ensembl | MGI Sequence Detail 948 Not Applicable  
    polypeptide ENSMUSP00000008594 Ensembl | MGI Sequence Detail 127 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 18
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2142461, MGI:2142525, MGI:2147075
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 5
      Gene Ontology 8
      Phenotypes 14
    • Earliest
      J:66319 Black BE, et al., Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export. Mol Cell Biol. 1999 Dec;19(12):8616-24
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory