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Nacc2 Gene Detail
Summary
  • Symbol
    Nacc2
  • Name
    nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
  • Synonyms
    0610020I02Rik, Btbd14a, C030048H19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915241
    NCBI Gene: 67991
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25945547-26012823 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 18.29 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1517 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915241
 protein coding gene Chr2:25945547-26013232 (-)
129S1/SvImJ ENSMUSG00200051766
 protein coding gene Chr2:22929744-22997052 (-)
A/J ENSMUSG00195047338
 protein coding gene Chr2:23018335-23085919 (-)
AKR/J ENSMUSG00220048758
 protein coding gene Chr2:23136171-23203739 (-)
BALB/cJ ENSMUSG00180053961
 protein coding gene Chr2:23031421-23098708 (-)
C3H/HeJ ENSMUSG00175051131
 protein coding gene Chr2:22995562-23068154 (-)
C57BL/6NJ ENSMUSG00215044389
 protein coding gene Chr2:23054315-23121602 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023305
 protein coding gene Chr2:21950115-22021440 (-)
CAST/EiJ ENSTCUG00005051305
 protein coding gene Chr2:22757038-22829226 (-)
CBA/J ENSMUSG00210017503
 protein coding gene Chr2:23034514-23101805 (-)
DBA/2J ENSMUSG00185046782
 protein coding gene Chr2:22932506-23000062 (-)
FVB/NJ ENSMUSG00205049510
 protein coding gene Chr2:22788393-22855656 (-)
JF1/MsJ ENSUMUG00000050359
 protein coding gene Chr2:22836957-22905356 (-)
LP/J ENSMUSG00230043565
 protein coding gene Chr2:24865703-24933007 (-)
NOD/ShiLtJ ENSMUSG00190033274
 protein coding gene Chr2:23024894-23092168 (-)
NZO/HlLtJ ENSMUSG00225006673
 protein coding gene Chr2:32600571-32669162 (-)
PWK/PhJ ENSLUMG00010048600
 protein coding gene Chr2:22928622-22996960 (-)
SPRET/EiJ ENSMSPG00010044444
 protein coding gene Chr2:23620338-23688107 (-)
WSB/EiJ ENSIUOG00005046819
 protein coding gene Chr2:22889853-22957181 (-)



Homology
more
  • Human Ortholog
    NACC2, NACC family member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NACC2, NACC family member 2
  • Synonyms
    BEND9, BTBD14, BTBD14A, BTBD31, NAC-2, RBB
  • Links
    NCBI Gene ID: 138151
    UniProt: Q96BF6

  • Chr Location
    9q34.3; chr9:136006537-136095289 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    13
  • cDNA Data
    68
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67991 NCBI Gene Model | MGI Sequence Detail 67277 C57BL/6J ±  kb
    transcript NM_001037098 RefSeq | MGI Sequence Detail 6893 C57BL/6  
    polypeptide Q9DCM7 UniProt | EBI | MGI Sequence Detail 586 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 68
      cDNA 68

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1915386, MGI:2138951
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory