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Ufm1 Gene Detail
Summary
  • Symbol
    Ufm1
  • Name
    ubiquitin-fold modifier 1
  • Synonyms
    1810045K17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915140
    NCBI Gene: 67890
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:53760797-53771228 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 25.43 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    352 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915140
 protein coding gene Chr3:53760797-53771251 (-)
129S1/SvImJ ENSMUSG00200022270
 protein coding gene Chr3:50612471-50622925 (-)
A/J ENSMUSG00195029978
 protein coding gene Chr3:50548952-50559406 (-)
AKR/J ENSMUSG00220029486
 protein coding gene Chr3:50607924-50618378 (-)
BALB/cJ ENSMUSG00180000358
 protein coding gene Chr3:50628814-50639268 (-)
C3H/HeJ ENSMUSG00175002084
 protein coding gene Chr3:50468640-50479094 (-)
C57BL/6NJ ENSMUSG00215006015
 protein coding gene Chr3:50907002-50917456 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024987
 protein coding gene Chr3:47446930-47457747 (-)
CAST/EiJ ENSTCUG00005009202
 protein coding gene Chr3:50263567-50274049 (-)
CBA/J ENSMUSG00210000582
 protein coding gene Chr3:50590015-50600469 (-)
DBA/2J ENSMUSG00185027106
 protein coding gene Chr3:50805219-50815673 (-)
FVB/NJ ENSMUSG00205008639
 protein coding gene Chr3:49783550-49794004 (-)
JF1/MsJ ENSUMUG00000018443
 protein coding gene Chr3:50221359-50231847 (-)
LP/J ENSMUSG00230003582
 protein coding gene Chr3:52767152-52777606 (-)
NOD/ShiLtJ ENSMUSG00190032037
 protein coding gene Chr3:50943190-50953644 (-)
NZO/HlLtJ ENSMUSG00225016282
 protein coding gene Chr3:55379551-55390005 (-)
PWK/PhJ ENSLUMG00010009155
 protein coding gene Chr3:50362038-50372509 (-)
SPRET/EiJ ENSMSPG00010007355
 protein coding gene Chr3:51056339-51067916 (-)
WSB/EiJ ENSIUOG00005008853
 protein coding gene Chr3:50726046-50736494 (-)



Homology
more
  • Human Ortholog
    UFM1, ubiquitin fold modifier 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UFM1, ubiquitin fold modifier 1
  • Synonyms
    BM-002, C13orf20, HLD14
  • Links
    NCBI Gene ID: 51569
    UniProt: P61960

  • Chr Location
    13q13.3; chr13:38349826-38363619 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human UFM1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    2
  • cDNA Data
    116
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67890 NCBI Gene Model | MGI Sequence Detail 10432 C57BL/6J ±  kb
    transcript NM_026435 RefSeq | MGI Sequence Detail 4887 C57BL/6  
    polypeptide P61961 UniProt | EBI | MGI Sequence Detail 85 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 117
      cDNA 116
      Primer pair 1

      Microarray probesets 12
    Other
    Accession IDs
    less
    MGI:2139638, MGI:2139733, MGI:3642188
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 10
      Phenotypes 13
    • Earliest
      J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
    • Latest
      J:389100 Mao G, et al., The UFSP2-ODR4 complex spatially confines and dynamically controls UFM1 deconjugation to safeguard neuronal proteostasis. Mol Cell. 2026 Jul 9;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory