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Snx2 Gene Detail
Summary
  • Symbol
    Snx2
  • Name
    sorting nexin 2
  • Synonyms
    0610030A03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915054
    NCBI Gene: 67804
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:53309388-53353937 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 28.99 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    907 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915054
 protein coding gene Chr18:53309362-53353938 (+)
129S1/SvImJ ENSMUSG00200027999
 protein coding gene Chr18:50348411-50392988 (+)
A/J ENSMUSG00195024223
 protein coding gene Chr18:50508891-50553448 (+)
AKR/J ENSMUSG00220021116
 protein coding gene Chr18:50489320-50533873 (+)
BALB/cJ ENSMUSG00180007304
 protein coding gene Chr18:51075338-51119896 (+)
C3H/HeJ ENSMUSG00175010923
 protein coding gene Chr18:50684392-50728943 (+)
C57BL/6NJ ENSMUSG00215007799
 protein coding gene Chr18:50030967-50075518 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022277
 protein coding gene Chr18:50092756-50140980 (+)
CAST/EiJ ENSTCUG00005013355
 protein coding gene Chr18:49892946-49936572 (+)
CBA/J ENSMUSG00210022465
 protein coding gene Chr18:50611771-50656307 (+)
DBA/2J ENSMUSG00185027326
 protein coding gene Chr18:50531809-50576354 (+)
FVB/NJ ENSMUSG00205012193
 protein coding gene Chr18:49973389-50017940 (+)
JF1/MsJ ENSUMUG00000020024
 protein coding gene Chr18:50452773-50497729 (+)
LP/J ENSMUSG00230011314
 protein coding gene Chr18:52527745-52572319 (+)
NOD/ShiLtJ ENSMUSG00190027119
 protein coding gene Chr18:50252649-50297201 (+)
NZO/HlLtJ ENSMUSG00225034227
 protein coding gene Chr18:52442458-52486977 (+)
PWK/PhJ ENSLUMG00010020474
 protein coding gene Chr18:50605456-50650409 (+)
SPRET/EiJ ENSMSPG00010017451
 protein coding gene Chr18:50940287-50985193 (+)
WSB/EiJ ENSIUOG00005008887
 protein coding gene Chr18:50147472-50190673 (+)



Homology
more
  • Human Ortholog
    SNX2, sorting nexin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNX2, sorting nexin 2
  • Synonyms
    TRG-9
  • Links
    NCBI Gene ID: 6643
    UniProt: O60749

  • Chr Location
    5q23.2; chr5:122774996-122834543 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    22 phenotypes from multigenic genotypes
    10 phenotype references
Homozygous mutant mice are viable and fertile and do not exhibit any apparent abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    48
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    6
  • cDNA Data
    235
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034484 Ensembl Gene Model | MGI Sequence Detail 44550 C57BL/6J ±  kb
transcript ENSMUST00000037850 Ensembl | MGI Sequence Detail 2067 Not Applicable  
polypeptide ENSMUSP00000039243 Ensembl | MGI Sequence Detail 519 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 239
    cDNA 235
    Primer pair 4

    Microarray probesets 3
References
more
  • Summaries
    All 47
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 10
  • Earliest
    J:22350 Yuan L, et al., Rapid cDNA sequencing in combination with RNA expression studies in mice identifies a large number of male germ cell-specific sequence tags. Biol Reprod. 1995 Jan;52(1):131-8
  • Latest
    J:345099 Wang X, et al., Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development. BMC Genomics. 2024 Feb 3;25(1):139
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory