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Lce1h Gene Detail
Summary
  • Symbol
    Lce1h
  • Name
    late cornified envelope 1H
  • Synonyms
    2310066F03Rik, Sprrl9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914968
    NCBI Gene: 67718
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92670522-92672372 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914968
 protein coding gene Chr3:92670522-92672372 (-)
129S1/SvImJ ENSMUSG00200037358
 protein coding gene Chr3:89458131-89459981 (-)
A/J ENSMUSG00195053120
 protein coding gene Chr3:89467443-89469293 (-)
AKR/J ENSMUSG00220049133
 protein coding gene Chr3:88688678-88690528 (-)
BALB/cJ ENSMUSG00180047895
 protein coding gene Chr3:89631145-89632995 (-)
C3H/HeJ ENSMUSG00175047098
 protein coding gene Chr3:89405255-89407105 (-)
C57BL/6NJ ENSMUSG00215046934
 protein coding gene Chr3:90017034-90018884 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025283
 protein coding gene Chr3:86942787-86943274 (-)
CAST/EiJ ENSTCUG00005042516
 protein coding gene Chr3:89790892-89792754 (-)
CBA/J ENSMUSG00210046699
 protein coding gene Chr3:89520386-89522236 (-)
DBA/2J ENSMUSG00185052323
 protein coding gene Chr3:89722766-89724616 (-)
FVB/NJ ENSMUSG00205043366
 protein coding gene Chr3:88514690-88516540 (-)
JF1/MsJ ENSUMUG00000039686
 protein coding gene Chr3:89282483-89284319 (-)
LP/J ENSMUSG00230040134
 protein coding gene Chr3:91755602-91757452 (-)
NOD/ShiLtJ ENSMUSG00190046208
 protein coding gene Chr3:89841037-89842898 (-)
NZO/HlLtJ ENSMUSG00225008289
 protein coding gene Chr3:94603331-94605181 (-)
PWK/PhJ ENSLUMG00010041757
 protein coding gene Chr3:89335708-89337549 (-)
SPRET/EiJ ENSMSPG00010048521
 protein coding gene Chr3:89785479-89787308 (-)
WSB/EiJ ENSIUOG00005046350
 protein coding gene Chr3:89992840-89994701 (-)



Homology
more
  • Human Ortholog
    LCE1A, late cornified envelope 1A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LCE1A, late cornified envelope 1A
  • Synonyms
    LEP1
  • Links
    NCBI Gene ID: 353131
    UniProt: Q5T7P2

  • Chr Location
    1q21.3; chr1:152827473-152828097 (+)  GRCh38
  • Human Ortholog
    LCE1D, late cornified envelope 1D
  • Synonyms
    LEP4
  • Links
    NCBI Gene ID: 353134
    UniProt: Q5T752

  • Chr Location
    1q21.3; chr1:152796721-152798181 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Lce1h
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    4
  • cDNA Data
    6
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67718 NCBI Gene Model | MGI Sequence Detail 1851 C57BL/6J ±  kb
transcript NM_026335 RefSeq | MGI Sequence Detail 706 C57BL/6  
polypeptide NP_080611 RefSeq | MGI Sequence Detail 140 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR028205 Late cornified envelope protein
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139700
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:341642 Schwartz B, et al., ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory