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Rpp21 Gene Detail
Summary
  • Symbol
    Rpp21
  • Name
    ribonuclease P 21 subunit
  • Synonyms
    0610037N01Rik, Rpp21
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914926
    NCBI Gene: 67676
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:36566565-36568738 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.01 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914926
 protein coding gene Chr17:36566537-36568961 (-)
129S1/SvImJ ENSMUSG00200047480
 protein coding gene Chr17:32168386-32170809 (-)
A/J ENSMUSG00195041750
 protein coding gene Chr17:33249772-33252198 (-)
AKR/J ENSMUSG00220051955
 protein coding gene Chr17:32041323-32043745 (-)
BALB/cJ ENSMUSG00180041393
 protein coding gene Chr17:32670031-32672454 (-)
C3H/HeJ ENSMUSG00175028176
 protein coding gene Chr17:31927116-31929537 (-)
C57BL/6NJ ENSMUSG00215053004
 protein coding gene Chr17:31996444-31998869 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021549
 protein coding gene Chr17:33329760-33332156 (-)
CAST/EiJ ENSTCUG00005050966
 protein coding gene Chr17:33064744-33067163 (-)
CBA/J ENSMUSG00210051980
 protein coding gene Chr17:31749117-31751538 (-)
DBA/2J ENSMUSG00185050661
 protein coding gene Chr17:34689162-34691584 (-)
FVB/NJ ENSMUSG00205022376
 protein coding gene Chr17:32305961-32308387 (-)
JF1/MsJ ENSUMUG00000033711
 protein coding gene Chr17:33648409-33650841 (-)
LP/J ENSMUSG00230054136
 protein coding gene Chr17:35834877-35837299 (-)
NOD/ShiLtJ ENSMUSG00190033948
 protein coding gene Chr17:31925039-31927464 (-)
NZO/HlLtJ ENSMUSG00225052610
 protein coding gene Chr17:37753121-37755540 (-)
PWK/PhJ ENSLUMG00010042310
 protein coding gene Chr17:31486825-31489251 (-)
SPRET/EiJ ENSMSPG00010034909
 protein coding gene Chr17:32808839-32811192 (-)
WSB/EiJ ENSIUOG00005044843
 protein coding gene Chr17:32821055-32823483 (-)



Homology
more
  • Human Ortholog
    RPP21, ribonuclease P subunit p21
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPP21, ribonuclease P subunit p21
  • Synonyms
    C6orf135, CAT60
  • Links
    NCBI Gene ID: 79897
    UniProt: Q9H633

  • Chr Location
    6p22.1; chr6:30345125-30346884 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    50
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67676 NCBI Gene Model | MGI Sequence Detail 2174 C57BL/6J ±  kb
transcript NM_026308 RefSeq | MGI Sequence Detail 500 C57BL/6  
polypeptide Q8R040 UniProt | EBI | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory