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Spc24 Gene Detail
Summary
  • Symbol
    Spc24
  • Name
    SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
  • Synonyms
    2410030K01Rik, Spbc24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914879
    NCBI Gene: 67629
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:21666738-21671599 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 7.88 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    233 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914879
 protein coding gene Chr9:21666730-21671741 (-)
129S1/SvImJ ENSMUSG00200047090
 protein coding gene Chr9:18620983-18625844 (-)
A/J ENSMUSG00195037479
 protein coding gene Chr9:18457592-18462454 (-)
AKR/J ENSMUSG00220028742
 protein coding gene Chr9:18460032-18464893 (-)
BALB/cJ ENSMUSG00180035701
 protein coding gene Chr9:18591890-18596752 (-)
C3H/HeJ ENSMUSG00175041773
 protein coding gene Chr9:18554439-18559300 (-)
C57BL/6NJ ENSMUSG00215036434
 protein coding gene Chr9:18551730-18556591 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031881
 protein coding gene Chr9:17765412-17770791 (-)
CAST/EiJ ENSTCUG00005032890
 protein coding gene Chr9:18602670-18608273 (-)
CBA/J ENSMUSG00210032898
 protein coding gene Chr9:18535367-18540228 (-)
DBA/2J ENSMUSG00185026034
 protein coding gene Chr9:18650662-18655523 (-)
FVB/NJ ENSMUSG00205040861
 protein coding gene Chr9:18879259-18883969 (-)
JF1/MsJ ENSUMUG00000035507
 protein coding gene Chr9:18757221-18762062 (-)
LP/J ENSMUSG00230040149
 protein coding gene Chr9:19038492-19043201 (-)
NOD/ShiLtJ ENSMUSG00190039538
 protein coding gene Chr9:18572242-18576952 (-)
NZO/HlLtJ ENSMUSG00225048546
 protein coding gene Chr9:18992649-18997510 (-)
PWK/PhJ ENSLUMG00010038440
 protein coding gene Chr9:18649433-18654274 (-)
SPRET/EiJ ENSMSPG00010021933
 protein coding gene Chr9:18881368-18885466 (-)
WSB/EiJ ENSIUOG00005039122
 protein coding gene Chr9:18120690-18125399 (-)



Homology
more
  • Human Ortholog
    SPC24, SPC24 component of NDC80 kinetochore complex
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPC24, SPC24 component of NDC80 kinetochore complex
  • Synonyms
    SPBC24
  • Links
    NCBI Gene ID: 147841
    UniProt: Q8NBT2

  • Chr Location
    19p13.2; chr19:11131520-11155807 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    642
  • Tissues
    9
  • cDNA Data
    50
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074476 Ensembl Gene Model | MGI Sequence Detail 4862 C57BL/6J ±  kb
transcript ENSMUST00000098942 Ensembl | MGI Sequence Detail 1366 Not Applicable  
polypeptide ENSMUSP00000096541 Ensembl | MGI Sequence Detail 201 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 50
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143262
References
more
  • Summaries
    All 43
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:314103 Ulmke PA, et al., Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory