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Ccdc127 Gene Detail
Summary
  • Symbol
    Ccdc127
  • Name
    coiled-coil domain containing 127
  • Synonyms
    0610011N22Rik, 5430420E17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914683
    NCBI Gene: 67433
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:74498436-74513902 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 40.17 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    515 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914683
 protein coding gene Chr13:74498428-74513902 (+)
129S1/SvImJ ENSMUSG00200011289
 protein coding gene Chr13:68902985-68918424 (+)
A/J ENSMUSG00195028500
 protein coding gene Chr13:69477649-69493092 (+)
AKR/J ENSMUSG00220030871
 protein coding gene Chr13:68068790-68084235 (+)
BALB/cJ ENSMUSG00180021505
 protein coding gene Chr13:69975971-69991413 (+)
C3H/HeJ ENSMUSG00175006936
 protein coding gene Chr13:70254256-70269700 (+)
C57BL/6NJ ENSMUSG00215005769
 protein coding gene Chr13:70042217-70057696 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018721
 protein coding gene Chr13:69008944-69024190 (+)
CAST/EiJ ENSTCUG00005011546
 protein coding gene Chr13:69558162-69573633 (+)
CBA/J ENSMUSG00210008146
 protein coding gene Chr13:69577509-69592986 (+)
DBA/2J ENSMUSG00185017968
 protein coding gene Chr13:73269059-73284534 (+)
FVB/NJ ENSMUSG00205018399
 protein coding gene Chr13:68956170-68971611 (+)
JF1/MsJ ENSUMUG00000015893
 protein coding gene Chr13:73028841-73044312 (+)
LP/J ENSMUSG00230024005
 protein coding gene Chr13:83187729-83203211 (+)
NOD/ShiLtJ ENSMUSG00190033541
 protein coding gene Chr13:69576184-69591619 (+)
NZO/HlLtJ ENSMUSG00225027849
 protein coding gene Chr13:75694737-75710178 (+)
PWK/PhJ ENSLUMG00010011469
 protein coding gene Chr13:69070084-69085464 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005020258
 protein coding gene Chr13:68828592-68844060 (+)



Homology
more
  • Human Ortholog
    CCDC127, coiled-coil domain containing 127
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC127, coiled-coil domain containing 127
  • Links
    NCBI Gene ID: 133957
    UniProt: Q96BQ5

  • Chr Location
    5p15.33; chr5:196868-218153 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67433 NCBI Gene Model | MGI Sequence Detail 15467 C57BL/6J ±  kb
    transcript NM_001168658 RefSeq | MGI Sequence Detail 5764 C57BL/6  
    polypeptide Q3TC33 UniProt | EBI | MGI Sequence Detail 260 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000031014 coiled-coil domain-containing protein 127
      (term hierarchy)
    • InterPro Domains
      IPR034607 Coiled-coil domain-containing protein 127
    • GlyGen
      Q3TC33 1 site, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1918606, MGI:2145196, MGI:2145408
    References
    more
    • Summaries
      All 42
      Gene Ontology 4
      Phenotypes 14
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory