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Carnmt1 Gene Detail
Summary
  • Symbol
    Carnmt1
  • Name
    carnosine N-methyltransferase 1
  • Synonyms
    2410127L17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914633
    NCBI Gene: 67383
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:18648128-18684564 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 13.18 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1095 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914633
 protein coding gene Chr19:18648099-18684565 (+)
129S1/SvImJ ENSMUSG00200020639
 protein coding gene Chr19:15329332-15365711 (+)
A/J ENSMUSG00195017393
 protein coding gene Chr19:15484886-15520614 (+)
A/J ENSMUSG00195010576
 protein coding gene Chr9:75656152-75659185 (-)
AKR/J ENSMUSG00220010236
 protein coding gene Chr19:15462739-15499141 (+)
AKR/J ENSMUSG00220014676
 protein coding gene Chr9:75762407-75765479 (-)
BALB/cJ ENSMUSG00180018148
 protein coding gene Chr19:15853323-15889677 (+)
BALB/cJ ENSMUSG00180015827
 protein coding gene Chr9:75769462-75772726 (-)
C3H/HeJ ENSMUSG00175003709
 protein coding gene Chr19:15193181-15228907 (+)
C3H/HeJ ENSMUSG00175011590
 protein coding gene Chr9:75828492-75831525 (-)
C57BL/6NJ ENSMUSG00215011008
 protein coding gene Chr9:75713262-75716405 (-)
C57BL/6NJ ENSMUSG00215013620
 protein coding gene Chr19:15254483-15290923 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022805
 protein coding gene Chr19:15991004-16022913 (+)
CAST/EiJ ENSTCUG00005008252
 protein coding gene Chr19:15094831-15131389 (+)
CBA/J ENSMUSG00210012618
 protein coding gene Chr19:15427720-15463437 (+)
CBA/J ENSMUSG00210013251
 protein coding gene Chr9:75861404-75864437 (-)
DBA/2J ENSMUSG00185013542
 protein coding gene Chr19:15842403-15878760 (+)
DBA/2J ENSMUSG00185006538
 protein coding gene Chr9:75889508-75892772 (-)
FVB/NJ ENSMUSG00205003820
 protein coding gene Chr19:15253258-15289635 (+)
FVB/NJ ENSMUSG00205017055
 protein coding gene Chr9:76050291-76053555 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230015747
 protein coding gene Chr19:16698518-16734896 (+)
NOD/ShiLtJ ENSMUSG00190019204
 protein coding gene Chr19:15208371-15244088 (+)
NOD/ShiLtJ ENSMUSG00190031043
 protein coding gene Chr9:75965825-75968858 (-)
NZO/HlLtJ ENSMUSG00225025039
 protein coding gene Chr9:76187308-76190702 (-)
PWK/PhJ ENSLUMG00010008419
 protein coding gene Chr19:15402697-15440006 (+)
SPRET/EiJ ENSMSPG00010017850
 protein coding gene Chr19:15402274-15437184 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CARNMT1, carnosine N-methyltransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CARNMT1, carnosine N-methyltransferase 1
  • Synonyms
    C9orf41, UPF0586
  • Links
    NCBI Gene ID: 138199
    UniProt: Q8N4J0

  • Chr Location
    9q21.13; chr9:74980790-75028437 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 3 alleles in 3 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Micr homozygous for a null or catalytically inactive allele die between E13.5 and E15.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    627
  • Tissues
    9
  • cDNA Data
    11
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024726 Ensembl Gene Model | MGI Sequence Detail 36437 C57BL/6J ±  kb
    transcript ENSMUST00000025632 Ensembl | MGI Sequence Detail 4518 Not Applicable  
    polypeptide ENSMUSP00000025632 Ensembl | MGI Sequence Detail 400 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1
      Antibodies 1

      Microarray probesets 7
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 1
      Gene Ontology 10
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:378174 Yan B, et al., Embryonic Lethal Phenotyping to Identify Candidate Genes Related with Birth Defects. Int J Mol Sci. 2024 Aug 13;25(16)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory