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Larp1b Gene Detail
Summary
  • Symbol
    Larp1b
  • Name
    La ribonucleoprotein 1B
  • Synonyms
    1700108L22Rik, 4933421B21Rik, Larp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914604
    NCBI Gene: 214048
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:40904263-40994669 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 19.61 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2352 from dbSNP Build 142
  • Strain Annotations
    30
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914604
 protein coding gene Chr3:40904198-40994669 (+)
129S1/SvImJ ENSMUSG00200005768
 protein coding gene Chr3:37647867-37675830 (+)
129S1/SvImJ ENSMUSG00200005787
 protein coding gene Chr3:37720576-37738227 (+)
A/J ENSMUSG00195001398
 protein coding gene Chr3:37632191-37660163 (+)
A/J ENSMUSG00195001399
 protein coding gene Chr3:37704931-37722592 (+)
AKR/J ENSMUSG00220000397
 protein coding gene Chr3:37786858-37804503 (+)
AKR/J ENSMUSG00220000396
 protein coding gene Chr3:37714127-37742096 (+)
BALB/cJ ENSMUSG00180002301
 protein coding gene Chr3:37832057-37849707 (+)
BALB/cJ ENSMUSG00180002299
 protein coding gene Chr3:37759344-37787311 (+)
C3H/HeJ ENSMUSG00175003137
 protein coding gene Chr3:37702803-37720454 (+)
C3H/HeJ ENSMUSG00175003133
 protein coding gene Chr3:37630071-37658038 (+)
C57BL/6NJ ENSMUSG00215001488
 protein coding gene Chr3:38041852-38069820 (+)
C57BL/6NJ ENSMUSG00215001489
 protein coding gene Chr3:38114582-38132232 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024962
 protein coding gene Chr3:35491763-35593158 (+)
CAST/EiJ ENSTCUG00005000954
 protein coding gene Chr3:37486763-37515577 (+)
CBA/J ENSMUSG00210001079
 protein coding gene Chr3:37725490-37753455 (+)
CBA/J ENSMUSG00210001096
 protein coding gene Chr3:37798220-37815879 (+)
DBA/2J ENSMUSG00185001054
 protein coding gene Chr3:37922098-37950060 (+)
DBA/2J ENSMUSG00185001066
 protein coding gene Chr3:37994807-38012456 (+)
FVB/NJ ENSMUSG00205000526
 protein coding gene Chr3:37114116-37131757 (+)
FVB/NJ ENSMUSG00205000517
 protein coding gene Chr3:37041382-37069355 (+)
JF1/MsJ ENSUMUG00000000527
 protein coding gene Chr3:37416804-37452688 (+)
LP/J ENSMUSG00230022299
 protein coding gene Chr3:39961550-39979199 (+)
LP/J ENSMUSG00230022063
 protein coding gene Chr3:39888844-39916807 (+)
NOD/ShiLtJ ENSMUSG00190001152
 protein coding gene Chr3:38052119-38069766 (+)
NOD/ShiLtJ ENSMUSG00190001149
 protein coding gene Chr3:37979393-38007359 (+)
NZO/HlLtJ ENSMUSG00225000347
 protein coding gene Chr3:42509786-42537748 (+)
NZO/HlLtJ ENSMUSG00225000352
 protein coding gene Chr3:42582492-42600143 (+)
PWK/PhJ ENSLUMG00010000659
 protein coding gene Chr3:37460694-37489065 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005013477
 protein coding gene Chr3:37898387-37926354 (+)



Homology
more
  • Human Ortholog
    LARP1B, La ribonucleoprotein 1B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LARP1B, La ribonucleoprotein 1B
  • Synonyms
    LARP2
  • Links
    NCBI Gene ID: 55132
    UniProt: Q659C4

  • Chr Location
    4q28.2; chr4:128060789-128222931 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025762 Ensembl Gene Model | MGI Sequence Detail 90407 C57BL/6J ±  kb
transcript ENSMUST00000048490 Ensembl | MGI Sequence Detail 2497 Not Applicable  
polypeptide ENSMUSP00000037127 Ensembl | MGI Sequence Detail 541 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    12 Sequences
  • InterPro Domains
    IPR045180 La domain containing protein
    IPR006607 LARP1-like, DM15 repeat
    IPR006630 La-type HTH domain
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
  • GlyGen
    F6U5V1 1 site
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 6
Other
Accession IDs
less
MGI:1918324, MGI:2139606
References
more
  • Summaries
    All 36
    Diseases 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory