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Dipk1a Gene Detail
Summary
  • Symbol
    Dipk1a
  • Name
    divergent protein kinase domain 1A
  • Synonyms
    2900024C23Rik, Fam69a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914516
    NCBI Gene: 67266
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:108055919-108134951 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 52.23 cM, cytoband E5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1873 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914516
protein coding gene Chr5:108055908-108134951 (-)
129S1/SvImJ ENSMUSG00200005525
protein coding gene Chr5:101803868-101878153 (-)
A/J ENSMUSG00195033598
protein coding gene Chr5:101261910-101340943 (-)
AKR/J ENSMUSG00220033752
protein coding gene Chr5:100814560-100888860 (-)
BALB/cJ ENSMUSG00180032733
protein coding gene Chr5:101419528-101493823 (-)
C3H/HeJ ENSMUSG00175039104
protein coding gene Chr5:103451416-103528120 (-)
C57BL/6NJ ENSMUSG00215013312
protein coding gene Chr5:101458811-101537858 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027512
protein coding gene Chr5:100808320-100882091 (-)
CAST/EiJ ENSTCUG00005021733
protein coding gene Chr5:100696687-100772498 (-)
CBA/J ENSMUSG00210043177
protein coding gene Chr5:102209030-102285696 (-)
DBA/2J ENSMUSG00185044916
protein coding gene Chr5:105117993-105197259 (-)
FVB/NJ ENSMUSG00205030146
protein coding gene Chr5:101131571-101208308 (-)
JF1/MsJ ENSUMUG00000016137
protein coding gene Chr5:108175137-108252116 (-)
LP/J ENSMUSG00230026771
protein coding gene Chr5:109344962-109419242 (-)
NOD/ShiLtJ ENSMUSG00190032113
protein coding gene Chr5:101118998-101193465 (-)
NZO/HlLtJ ENSMUSG00225025046
protein coding gene Chr5:116966825-117041098 (-)
PWK/PhJ ENSLUMG00010014929
protein coding gene Chr5:100166899-100244202 (-)
SPRET/EiJ ENSMSPG00010037716
protein coding gene Chr5:103267641-103342890 (-)
WSB/EiJ ENSIUOG00005043243
protein coding gene Chr5:103836472-103915466 (-)



Homology
more
  • Human Ortholog
    DIPK1A, divergent protein kinase domain 1A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DIPK1A, divergent protein kinase domain 1A
  • Synonyms
    FAM69A
  • Links
    NCBI Gene ID: 388650
    UniProt: Q5T7M9

  • Chr Location
    1p22.1; chr1:92832729-92961522 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029270 Ensembl Gene Model | MGI Sequence Detail 79033 C57BL/6J ±  kb
    transcript ENSMUST00000031198 Ensembl | MGI Sequence Detail 2721 Not Applicable  
    polypeptide ENSMUSP00000031198 Ensembl | MGI Sequence Detail 428 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2140830, MGI:6276589
    References
    more
    • Summaries
      All 41
      Gene Ontology 2
      Phenotypes 15
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    09/01/2026
    MGI 6.24
    The Jackson Laboratory