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Gemin6 Gene Detail
Summary
  • Symbol
    Gemin6
  • Name
    gem nuclear organelle associated protein 6
  • Synonyms
    2610019B15Rik, 2810470M17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914492
    NCBI Gene: 67242
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:80531870-80535926 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 50.63 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    195 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914492
 protein coding gene Chr17:80514933-80535926 (+)
129S1/SvImJ ENSMUSG00200023096
 protein coding gene Chr17:75899602-75929675 (+)
A/J ENSMUSG00195026999
 protein coding gene Chr17:77252887-77301522 (+)
AKR/J ENSMUSG00220012806
 protein coding gene Chr17:76186270-76215507 (+)
BALB/cJ ENSMUSG00180004580
 protein coding gene Chr17:76972890-77002992 (+)
C3H/HeJ ENSMUSG00175014541
 protein coding gene Chr17:76243905-76274004 (+)
C57BL/6NJ ENSMUSG00215012007
 protein coding gene Chr17:75959570-75989691 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030803
 protein coding gene Chr8:1794898-1796196 (-)
CAST/EiJ ENSTCUG00005015135
 protein coding gene Chr17:76836054-76840138 (+)
CBA/J ENSMUSG00210019896
 protein coding gene Chr17:76105318-76135426 (+)
DBA/2J ENSMUSG00185012631
 protein coding gene Chr17:78938856-78968960 (+)
FVB/NJ ENSMUSG00205023595
 protein coding gene Chr17:76720986-76751102 (+)
JF1/MsJ ENSUMUG00000009361
 protein coding gene Chr17:78647977-78694808 (+)
LP/J ENSMUSG00230021487
 protein coding gene Chr17:79940334-79970444 (+)
NOD/ShiLtJ ENSMUSG00190009283
 protein coding gene Chr17:76005681-76035783 (+)
NZO/HlLtJ ENSMUSG00225030411
 protein coding gene Chr17:82198464-82245317 (+)
PWK/PhJ ENSLUMG00010005139
 protein coding gene Chr17:75885857-75915147 (+)
SPRET/EiJ ENSMSPG00010007959
 protein coding gene Chr17:76366231-76388434 (+)
WSB/EiJ ENSIUOG00005009956
 protein coding gene Chr17:76930031-76967483 (+)



Homology
more
  • Human Ortholog
    GEMIN6, gem nuclear organelle associated protein 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GEMIN6, gem nuclear organelle associated protein 6
  • Links
    NCBI Gene ID: 79833
    UniProt: Q8WXD5

  • Chr Location
    2p22.1; chr2:38751534-38785002 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    1 images
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit complete embryonic lethality between implantation and somite formation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    609
  • Tissues
    6
  • cDNA Data
    44
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055760 Ensembl Gene Model | MGI Sequence Detail 4057 C57BL/6J ±  kb
transcript ENSMUST00000069486 Ensembl | MGI Sequence Detail 1134 Not Applicable  
polypeptide ENSMUSP00000063554 Ensembl | MGI Sequence Detail 166 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44
    Antibodies 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916458
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory