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L3hypdh Gene Detail
Summary
  • Symbol
    L3hypdh
  • Name
    L-3-hydroxyproline dehydratase (trans-)
  • Synonyms
    2810055F11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914467
    NCBI Gene: 67217
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:72120202-72132213 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 30.20 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    511 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914467
 protein coding gene Chr12:72114745-72132213 (-)
129S1/SvImJ ENSMUSG00200029834
 protein coding gene Chr12:64028779-64041405 (-)
A/J ENSMUSG00195013534
 protein coding gene Chr12:66733337-66745350 (-)
AKR/J ENSMUSG00220014731
 protein coding gene Chr12:64539104-64551116 (-)
BALB/cJ ENSMUSG00180031758
 protein coding gene Chr12:65732372-65744385 (-)
C3H/HeJ ENSMUSG00175025505
 protein coding gene Chr12:68859226-68871237 (-)
C57BL/6NJ ENSMUSG00215022829
 protein coding gene Chr12:65110392-65122406 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017831
 protein coding gene Chr12:66697872-66710108 (-)
CAST/EiJ ENSTCUG00005031679
 protein coding gene Chr12:65038434-65050611 (-)
CBA/J ENSMUSG00210027278
 protein coding gene Chr12:65296538-65308549 (-)
DBA/2J ENSMUSG00185004671
 protein coding gene Chr12:67199565-67211576 (-)
FVB/NJ ENSMUSG00205021288
 protein coding gene Chr12:64924083-64936092 (-)
JF1/MsJ ENSUMUG00000011994
 protein coding gene Chr12:71143799-71155785 (-)
LP/J ENSMUSG00230014850
 protein coding gene Chr12:74164813-74177437 (-)
NOD/ShiLtJ ENSMUSG00190011624
 protein coding gene Chr12:64362661-64374676 (-)
NZO/HlLtJ ENSMUSG00225037500
 protein coding gene Chr12:76216267-76228890 (-)
PWK/PhJ ENSLUMG00010028999
 protein coding gene Chr12:65209120-65221095 (-)
SPRET/EiJ ENSMSPG00010027431
 protein coding gene Chr12:66913035-66925437 (-)
WSB/EiJ ENSIUOG00005011902
 protein coding gene Chr12:64987467-64999477 (-)



Homology
more
  • Human Ortholog
    L3HYPDH, trans-L-3-hydroxyproline dehydratase
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    L3HYPDH, trans-L-3-hydroxyproline dehydratase
  • Synonyms
    C14orf149
  • Links
    NCBI Gene ID: 112849
    UniProt: Q96EM0

  • Chr Location
    14q23.1; chr14:59460363-59505273 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving L3hypdh
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    28 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    7
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    24
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019718 Ensembl Gene Model | MGI Sequence Detail 12012 C57BL/6J ±  kb
transcript ENSMUST00000019862 Ensembl | MGI Sequence Detail 1831 Not Applicable  
polypeptide ENSMUSP00000019862 Ensembl | MGI Sequence Detail 354 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:187539 Visser WF, et al., Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes. J Biol Chem. 2012 Jun 22;287(26):21654-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory