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Actr6 Gene Detail
Summary
  • Symbol
    Actr6
  • Name
    ARP6 actin-related protein 6
  • Synonyms
    2010200J04Rik, Arp6, ArpX, CDA12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914269
    NCBI Gene: 67019
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:89547833-89568157 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 45.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    781 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914269
 protein coding gene Chr10:89547828-89568184 (-)
129S1/SvImJ ENSMUSG00200026213
 protein coding gene Chr10:86045800-86066126 (-)
A/J ENSMUSG00195018709
 protein coding gene Chr10:86496062-86516390 (-)
AKR/J ENSMUSG00220021170
 protein coding gene Chr10:86054695-86075019 (-)
BALB/cJ ENSMUSG00180031607
 protein coding gene Chr10:86498996-86519322 (-)
C3H/HeJ ENSMUSG00175021694
 protein coding gene Chr10:86379128-86399450 (-)
C57BL/6NJ ENSMUSG00215017966
 protein coding gene Chr10:86048560-86068884 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015720
 protein coding gene Chr10:83512801-83532177 (-)
CAST/EiJ ENSTCUG00005029306
 protein coding gene Chr10:85773909-85793819 (-)
CBA/J ENSMUSG00210030850
 protein coding gene Chr10:86219586-86239911 (-)
DBA/2J ENSMUSG00185041257
 protein coding gene Chr10:86437329-86458242 (-)
FVB/NJ ENSMUSG00205011937
 protein coding gene Chr10:86101005-86121333 (-)
JF1/MsJ ENSUMUG00000019403
 protein coding gene Chr10:87796818-87817737 (-)
LP/J ENSMUSG00230013548
 protein coding gene Chr10:88325931-88346253 (-)
NOD/ShiLtJ ENSMUSG00190017597
 protein coding gene Chr10:86481093-86501419 (-)
NZO/HlLtJ ENSMUSG00225020776
 protein coding gene Chr10:92604487-92624810 (-)
PWK/PhJ ENSLUMG00010021266
 protein coding gene Chr10:86103123-86124038 (-)
SPRET/EiJ ENSMSPG00010029986
 protein coding gene Chr10:87623555-87644612 (-)
WSB/EiJ ENSIUOG00005033670
 protein coding gene Chr10:86188069-86208375 (-)



Homology
more
  • Human Ortholog
    ACTR6, actin related protein 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACTR6, actin related protein 6
  • Synonyms
    ARP6, CDA12, hARP6, hARPX, HSPC281, MSTP136
  • Links
    NCBI Gene ID: 64431
    UniProt: Q9GZN1

  • Chr Location
    12q23.1; chr12:100199122-100241865 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    609
  • Tissues
    12
  • cDNA Data
    27
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000019948 Ensembl Gene Model | MGI Sequence Detail 20325 C57BL/6J ±  kb
    transcript ENSMUST00000020109 Ensembl | MGI Sequence Detail 1705 Not Applicable  
    polypeptide ENSMUSP00000020109 Ensembl | MGI Sequence Detail 396 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 27
      cDNA 27

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143768
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 15
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory