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Prl3a1 Gene Detail
Summary
  • Symbol
    Prl3a1
  • Name
    prolactin family 3, subfamily a, member 1
  • Synonyms
    1600016E11Rik, PLP-H, Plpi, PLP-I, Prlpi
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914250
    NCBI Gene: 67000
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:27443472-27460669 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.36 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    524 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914250
 protein coding gene Chr13:27443419-27460669 (+)
129S1/SvImJ ENSMUSG00200028693
 protein coding gene Chr13:24603145-24620376 (+)
A/J ENSMUSG00195037186
 protein coding gene Chr13:23741329-23758560 (+)
AKR/J ENSMUSG00220012634
 protein coding gene Chr13:23550851-23568084 (+)
BALB/cJ ENSMUSG00180020439
 protein coding gene Chr13:24046577-24063809 (+)
C3H/HeJ ENSMUSG00175030526
 protein coding gene Chr13:24069247-24086478 (+)
C57BL/6NJ ENSMUSG00215007171
 protein coding gene Chr13:24208244-24225475 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018365
 protein coding gene Chr13:22979778-22990704 (+)
CAST/EiJ ENSTCUG00005009619
 protein coding gene Chr13:24225032-24242054 (+)
CBA/J ENSMUSG00210026592
 protein coding gene Chr13:24013527-24030759 (+)
DBA/2J ENSMUSG00185018220
 protein coding gene Chr13:24835460-24852695 (+)
FVB/NJ ENSMUSG00205019174
 protein coding gene Chr13:23832654-23849887 (+)
JF1/MsJ ENSUMUG00000013540
 protein coding gene Chr13:24468441-24485457 (+)
LP/J ENSMUSG00230016590
 protein coding gene Chr13:34156857-34174089 (+)
NOD/ShiLtJ ENSMUSG00190034065
 protein coding gene Chr13:23817515-23834748 (+)
NZO/HlLtJ ENSMUSG00225044513
 protein coding gene Chr13:27943068-27960295 (+)
PWK/PhJ ENSLUMG00010027613
 protein coding gene Chr13:23304358-23321366 (+)
SPRET/EiJ ENSMSPG00010022715
 protein coding gene Chr13:23260054-23270877 (+)
WSB/EiJ ENSIUOG00005016090
 protein coding gene Chr13:23390516-23407895 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Prl3a1
  • Find Mice (IMSR)
    18 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    12
  • cDNA Data
    16
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67000 NCBI Gene Model | MGI Sequence Detail 17198 C57BL/6J ±  kb
transcript NM_025896 RefSeq | MGI Sequence Detail 1308 C57BL/6  
polypeptide NP_080172 RefSeq | MGI Sequence Detail 227 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR018116 Somatotropin hormone, conserved site
    IPR001400 Somatotropin/prolactin
  • GlyGen
    Q78Y73 1 site
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 42
    Developmental Gene Expression 9
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:333829 Lopez-Tello J, et al., Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age. Front Endocrinol (Lausanne). 2023;14:1116770
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory