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Aagab Gene Detail
Summary
  • Symbol
    Aagab
  • Name
    alpha- and gamma-adaptin binding protein
  • Synonyms
    2310007F21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914189
    NCBI Gene: 66939
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:63509942-63551870 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 34.19 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1264 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914189
 protein coding gene Chr9:63509897-63551872 (+)
129S1/SvImJ ENSMUSG00200035388
 protein coding gene Chr9:60612416-60654606 (+)
A/J ENSMUSG00195039580
 protein coding gene Chr9:60320989-60362937 (+)
AKR/J ENSMUSG00220026235
 protein coding gene Chr9:60470082-60513882 (+)
BALB/cJ ENSMUSG00180014833
 protein coding gene Chr9:60459622-60501542 (+)
C3H/HeJ ENSMUSG00175020607
 protein coding gene Chr9:60454087-60496031 (+)
C57BL/6NJ ENSMUSG00215029027
 protein coding gene Chr9:60446758-60488684 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032334
 protein coding gene Chr9:60771331-60810127 (+)
CAST/EiJ ENSTCUG00005019261
 protein coding gene Chr9:60363915-60405645 (+)
CBA/J ENSMUSG00210038822
 protein coding gene Chr9:60542461-60584379 (+)
DBA/2J ENSMUSG00185038658
 protein coding gene Chr9:60565654-60607576 (+)
FVB/NJ ENSMUSG00205031848
 protein coding gene Chr9:60891411-60933358 (+)
JF1/MsJ ENSUMUG00000047698
 protein coding gene Chr9:60623423-60663994 (+)
LP/J ENSMUSG00230033382
 protein coding gene Chr9:60811631-60853821 (+)
NOD/ShiLtJ ENSMUSG00190036618
 protein coding gene Chr9:60651013-60692963 (+)
NZO/HlLtJ ENSMUSG00225045901
 protein coding gene Chr9:60876861-60918809 (+)
PWK/PhJ ENSLUMG00010029613
 protein coding gene Chr9:60593584-60635604 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005032301
 protein coding gene Chr9:60057966-60099617 (+)



Homology
more
  • Human Ortholog
    AAGAB, alpha and gamma adaptin binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AAGAB, alpha and gamma adaptin binding protein
  • Synonyms
    KPPP1, p34, PPKP1, PPKP1A
  • Links
    NCBI Gene ID: 79719
    UniProt: Q6PD74

  • Chr Location
    15q23; chr15:67200667-67255198 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human AAGAB associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    627
  • Tissues
    3
  • cDNA Data
    76
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037257 Ensembl Gene Model | MGI Sequence Detail 41929 C57BL/6J ±  kb
transcript ENSMUST00000041551 Ensembl | MGI Sequence Detail 5294 Not Applicable  
polypeptide ENSMUSP00000048595 Ensembl | MGI Sequence Detail 316 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:381590 Jiang YW, et al., Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8538-43
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory