About   Help   FAQ
Pxdc1 Gene Detail
Summary
  • Symbol
    Pxdc1
  • Name
    PX domain containing 1
  • Synonyms
    1300014I06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914145
    NCBI Gene: 66895
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:34811823-34836664 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 14.16 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1076 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914145
 protein coding gene Chr13:34811817-34837469 (-)
129S1/SvImJ ENSMUSG00200012273
 protein coding gene Chr13:32007705-32033358 (-)
A/J ENSMUSG00195032102
 protein coding gene Chr13:31093166-31118838 (-)
AKR/J ENSMUSG00220027292
 protein coding gene Chr13:30882457-30908128 (-)
BALB/cJ ENSMUSG00180007524
 protein coding gene Chr13:31396967-31422638 (-)
C3H/HeJ ENSMUSG00175012284
 protein coding gene Chr13:31346214-31371884 (-)
C57BL/6NJ ENSMUSG00215008087
 protein coding gene Chr13:31536390-31562044 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018421
 protein coding gene Chr13:30085007-30110196 (-)
CAST/EiJ ENSTCUG00005030675
 protein coding gene Chr13:31418998-31444401 (-)
CBA/J ENSMUSG00210011115
 protein coding gene Chr13:31358719-31384388 (-)
DBA/2J ENSMUSG00185030113
 protein coding gene Chr13:32178121-32203791 (-)
FVB/NJ ENSMUSG00205028758
 protein coding gene Chr13:31066147-31091803 (-)
JF1/MsJ ENSUMUG00000021785
 protein coding gene Chr13:31761911-31787700 (-)
LP/J ENSMUSG00230015241
 protein coding gene Chr13:41502533-41528202 (-)
NOD/ShiLtJ ENSMUSG00190011361
 protein coding gene Chr13:31588245-31613898 (-)
NZO/HlLtJ ENSMUSG00225033631
 protein coding gene Chr13:35313520-35339189 (-)
PWK/PhJ ENSLUMG00010028178
 protein coding gene Chr13:30595561-30621369 (-)
SPRET/EiJ ENSMSPG00010010007
 protein coding gene Chr13:30491599-30517476 (-)
WSB/EiJ ENSIUOG00005027779
 protein coding gene Chr13:30742723-30768303 (-)



Homology
more
  • Human Ortholog
    PXDC1, PX domain containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PXDC1, PX domain containing 1
  • Synonyms
    C6orf145
  • Links
    NCBI Gene ID: 221749
    UniProt: Q5TGL8

  • Chr Location
    6p25.2; chr6:3722614-3751713 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Pxdc1
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    40
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66895 NCBI Gene Model | MGI Sequence Detail 24842 C57BL/6J ±  kb
transcript NR_168613 RefSeq | MGI Sequence Detail 2027 C57BL/6  
polypeptide Q8JZU6 UniProt | EBI | MGI Sequence Detail 231 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Gene Ontology 1
    Phenotypes 16
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory