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Spryd4 Gene Detail
Summary
  • Symbol
    Spryd4
  • Name
    SPRY domain containing 4
  • Synonyms
    4633402N23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913951
    NCBI Gene: 66701
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128045777-128047663 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 76.44 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913951
 protein coding gene Chr10:128045777-128047676 (-)
129S1/SvImJ ENSMUSG00200011864
 protein coding gene Chr10:124399305-124401206 (-)
A/J ENSMUSG00195015435
 protein coding gene Chr10:124862548-124864449 (-)
AKR/J ENSMUSG00220005069
 protein coding gene Chr10:124468167-124470068 (-)
BALB/cJ ENSMUSG00180009978
 protein coding gene Chr10:124853522-124855423 (-)
C3H/HeJ ENSMUSG00175005924
 protein coding gene Chr10:124853116-124855017 (-)
C57BL/6NJ ENSMUSG00215006622
 protein coding gene Chr10:124464178-124466077 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015923
 protein coding gene Chr10:120571977-120573863 (-)
CAST/EiJ ENSTCUG00005035157
 protein coding gene Chr10:123851559-123853462 (-)
CBA/J ENSMUSG00210008844
 protein coding gene Chr10:124677342-124679243 (-)
DBA/2J ENSMUSG00185023986
 protein coding gene Chr10:124831514-124833413 (-)
FVB/NJ ENSMUSG00205018404
 protein coding gene Chr10:124073408-124075309 (-)
JF1/MsJ ENSUMUG00000018914
 protein coding gene Chr10:126140089-126141990 (-)
LP/J ENSMUSG00230032230
 protein coding gene Chr10:126753228-126755129 (-)
NOD/ShiLtJ ENSMUSG00190014030
 protein coding gene Chr10:124895171-124897070 (-)
NZO/HlLtJ ENSMUSG00225036910
 protein coding gene Chr10:130955820-130957721 (-)
PWK/PhJ ENSLUMG00010008871
 protein coding gene Chr10:124592176-124594077 (-)
SPRET/EiJ ENSMSPG00010029323
 protein coding gene Chr10:126556849-126558750 (-)
WSB/EiJ ENSIUOG00005007898
 protein coding gene Chr10:124469548-124471447 (-)



Homology
more
  • Human Ortholog
    SPRYD4, SPRY domain containing 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPRYD4, SPRY domain containing 4
  • Links
    NCBI Gene ID: 283377
    UniProt: Q8WW59

  • Chr Location
    12q13.3; chr12:56468578-56479708 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    610
  • Tissues
    13
  • cDNA Data
    35
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66701 NCBI Gene Model | MGI Sequence Detail 1887 C57BL/6J ±  kb
    transcript NM_025716 RefSeq | MGI Sequence Detail 1570 C57BL/6  
    polypeptide Q91WK1 UniProt | EBI | MGI Sequence Detail 207 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 35
      cDNA 35

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3035447
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory