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Lrrc57 Gene Detail
Summary
  • Symbol
    Lrrc57
  • Name
    leucine rich repeat containing 57
  • Synonyms
    2810002D13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913856
    NCBI Gene: 66606
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120434719-120439989 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913856
 protein coding gene Chr2:120434719-120440001 (-)
129S1/SvImJ ENSMUSG00200045832
 protein coding gene Chr2:117378319-117383610 (-)
A/J ENSMUSG00195024275
 protein coding gene Chr2:117417912-117423193 (-)
AKR/J ENSMUSG00220040629
 protein coding gene Chr2:117342571-117347861 (-)
BALB/cJ ENSMUSG00180041374
 protein coding gene Chr2:117218530-117223811 (-)
C3H/HeJ ENSMUSG00175026826
 protein coding gene Chr2:117694230-117699521 (-)
C57BL/6NJ ENSMUSG00215011002
 protein coding gene Chr2:117352995-117358277 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024171
 protein coding gene Chr2:113436446-113441721 (-)
CAST/EiJ ENSTCUG00005016649
 protein coding gene Chr2:116628400-116633692 (-)
CBA/J ENSMUSG00210007254
 protein coding gene Chr2:117535183-117540474 (-)
DBA/2J ENSMUSG00185044191
 protein coding gene Chr2:117215890-117221171 (-)
FVB/NJ ENSMUSG00205035550
 protein coding gene Chr2:116443242-116448533 (-)
JF1/MsJ ENSUMUG00000033161
 protein coding gene Chr2:117101135-117106417 (-)
LP/J ENSMUSG00230019231
 protein coding gene Chr2:119037968-119043259 (-)
NOD/ShiLtJ ENSMUSG00190037661
 protein coding gene Chr2:117463403-117468694 (-)
NZO/HlLtJ ENSMUSG00225002167
 protein coding gene Chr2:126941789-126947080 (-)
PWK/PhJ ENSLUMG00010042313
 protein coding gene Chr2:116993827-116999134 (-)
SPRET/EiJ ENSMSPG00010034093
 protein coding gene Chr2:119419574-119424867 (-)
WSB/EiJ ENSIUOG00005023199
 protein coding gene Chr2:117191410-117196702 (-)



Homology
more
  • Human Ortholog
    LRRC57, leucine rich repeat containing 57
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC57, leucine rich repeat containing 57
  • Links
    NCBI Gene ID: 255252
    UniProt: Q8N9N7

  • Chr Location
    15q15.2; chr15:42528327-42548802 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Lrrc57
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    5 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    48
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66606 NCBI Gene Model | MGI Sequence Detail 5271 C57BL/6J ±  kb
transcript NM_001159612 RefSeq | MGI Sequence Detail 1982 C57BL/6  
polypeptide Q9D1G5 UniProt | EBI | MGI Sequence Detail 239 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    cDNA 48

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138742
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory