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Gtf3a Gene Detail
Summary
  • Symbol
    Gtf3a
  • Name
    general transcription factor III A
  • Synonyms
    2010015D03Rik, 2610111I01Rik, 5330403M05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913846
    NCBI Gene: 66596
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:146885467-146892424 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 86.57 cM, cytoband G2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    351 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913846
 protein coding gene Chr5:146885467-146892424 (+)
129S1/SvImJ ENSMUSG00200039433
 protein coding gene Chr5:140719799-140726756 (+)
A/J ENSMUSG00195044235
 protein coding gene Chr5:140324804-140331746 (+)
AKR/J ENSMUSG00220022811
 protein coding gene Chr5:139330976-139337947 (+)
BALB/cJ ENSMUSG00180026378
 protein coding gene Chr5:140707296-140714238 (+)
C3H/HeJ ENSMUSG00175011341
 protein coding gene Chr5:142548218-142555160 (+)
C57BL/6NJ ENSMUSG00215038956
 protein coding gene Chr5:140274831-140281788 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028031
 protein coding gene Chr5:140524499-140531452 (+)
CAST/EiJ ENSTCUG00005034149
 protein coding gene Chr5:139848033-139854966 (+)
CBA/J ENSMUSG00210023994
 protein coding gene Chr5:141467028-141473999 (+)
DBA/2J ENSMUSG00185038574
 protein coding gene Chr5:144436267-144443209 (+)
FVB/NJ ENSMUSG00205029629
 protein coding gene Chr5:140085267-140092233 (+)
JF1/MsJ ENSUMUG00000028963
 protein coding gene Chr5:146927498-146934442 (+)
LP/J ENSMUSG00230029120
 protein coding gene Chr5:148436716-148443673 (+)
NOD/ShiLtJ ENSMUSG00190042039
 protein coding gene Chr5:140078966-140085923 (+)
NZO/HlLtJ ENSMUSG00225007965
 protein coding gene Chr5:156181223-156188194 (+)
PWK/PhJ ENSLUMG00010019544
 protein coding gene Chr5:139164277-139171216 (+)
SPRET/EiJ ENSMSPG00010005756
 protein coding gene Chr5:141969747-141976717 (+)
WSB/EiJ ENSIUOG00005029188
 protein coding gene Chr5:142855094-142862036 (+)



Homology
more
  • Human Ortholog
    GTF3A, general transcription factor IIIA
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTF3A, general transcription factor IIIA
  • Synonyms
    AP2, TFIIIA
  • Links
    NCBI Gene ID: 2971
    UniProt: Q92664

  • Chr Location
    13q12.2; chr13:27424619-27435823 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    56
  • cDNA Data
    74
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66596 NCBI Gene Model | MGI Sequence Detail 6958 C57BL/6J ±  kb
transcript NM_025652 RefSeq | MGI Sequence Detail 1315 C57BL/6  
polypeptide Q8VHT7 UniProt | EBI | MGI Sequence Detail 364 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 76
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919733, MGI:1923924
References
more
  • Summaries
    All 43
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:190636 Wiese CB, et al., A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory