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Prrc2c Gene Detail
Summary
  • Symbol
    Prrc2c
  • Name
    proline-rich coiled-coil 2C
  • Synonyms
    1810043M20Rik, 9630039I18Rik, Bat2d, Bat2l2, mKIAA1096
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913754
    NCBI Gene: 226562
  • Alliance
    genome feature page
  • Transcription Start Sites
    25 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162499354-162568125 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 70.30 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1203 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913754
 protein coding gene Chr1:162498294-162568125 (-)
129S1/SvImJ ENSMUSG00200005437
 protein coding gene Chr1:159978554-160032687 (-)
A/J ENSMUSG00195020039
 protein coding gene Chr1:159318673-159372808 (-)
AKR/J ENSMUSG00220013116
 protein coding gene Chr1:159111533-159165681 (-)
BALB/cJ ENSMUSG00180033240
 protein coding gene Chr1:159567873-159621854 (-)
C3H/HeJ ENSMUSG00175042496
 protein coding gene Chr1:159645258-159699388 (-)
C57BL/6NJ ENSMUSG00215033435
 protein coding gene Chr1:159518659-159572805 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014775
 protein coding gene Chr1:153229774-153300816 (-)
CAST/EiJ ENSTCUG00005019410
 protein coding gene Chr1:158142658-158196851 (-)
CBA/J ENSMUSG00210020354
 protein coding gene Chr1:159524207-159578340 (-)
DBA/2J ENSMUSG00185011257
 protein coding gene Chr1:163785432-163839404 (-)
FVB/NJ ENSMUSG00205007922
 protein coding gene Chr1:158599450-158653598 (-)
JF1/MsJ ENSUMUG00000010000
 protein coding gene Chr1:162934830-162988815 (-)
LP/J ENSMUSG00230020435
 protein coding gene Chr1:163389021-163443152 (-)
NOD/ShiLtJ ENSMUSG00190036313
 protein coding gene Chr1:159357123-159411267 (-)
NZO/HlLtJ ENSMUSG00225002975
 protein coding gene Chr1:166979322-167033448 (-)
PWK/PhJ ENSLUMG00010042066
 protein coding gene Chr1:158323023-158377097 (-)
SPRET/EiJ ENSMSPG00010040613
 protein coding gene Chr1:161739608-161809724 (-)
WSB/EiJ ENSIUOG00005015415
 protein coding gene Chr1:158890594-158944709 (-)



Homology
more
  • Human Ortholog
    PRRC2C, proline rich coiled-coil 2C
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRRC2C, proline rich coiled-coil 2C
  • Synonyms
    BAT2D1, BAT2-iso, BAT2L2, XTP2
  • Links
    NCBI Gene ID: 23215
    UniProt: Q9Y520

  • Chr Location
    1q24.3; chr1:171485530-171593511 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    29
  • cDNA Data
    186
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 226562 NCBI Gene Model | MGI Sequence Detail 68772 C57BL/6J ±  kb
    transcript NM_001081290 RefSeq | MGI Sequence Detail 10444 Not Specified  
    polypeptide Q3TLH4 UniProt | EBI | MGI Sequence Detail 2846 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 190
      Genomic 2
      cDNA 187
      Primer pair 1

      Microarray probesets 11
    Other
    Accession IDs
    less
    MGI:2443690
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 5
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:40877 Wada J, et al., Representational difference analysis of cDNA of genes expressed in embryonic kidney. Kidney Int. 1997 May;51(5):1629-38
    • Latest
      J:347284 Zhang Y, et al., PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA. Cell Rep. 2024 Mar 26;43(3):113930
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory