About   Help   FAQ
Uqcc5 Gene Detail
Summary
  • Symbol
    Uqcc5
  • Name
    ubiquinol-cytochrome c reductase complex assembly factor 5
  • Synonyms
    Gm41122, Smim4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913737
    NCBI Gene: 66487
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30810081-30850894 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, Syntenic
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    777 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913737
 protein coding gene Chr14:30810081-30850913 (-)
129S1/SvImJ ENSMUSG00200037104
 protein coding gene Chr14:22632312-22672493 (-)
A/J ENSMUSG00195013465
 protein coding gene Chr14:23707298-23748142 (-)
AKR/J ENSMUSG00220030792
 protein coding gene Chr14:22819662-22860523 (-)
BALB/cJ ENSMUSG00180023487
 protein coding gene Chr14:22796409-22836680 (-)
C3H/HeJ ENSMUSG00175039591
 protein coding gene Chr14:22863719-22903984 (-)
C57BL/6NJ ENSMUSG00215025818
 protein coding gene Chr14:23102105-23142380 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019065
 protein coding gene Chr14:23409466-23445637 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210040088
 protein coding gene Chr14:23106631-23146887 (-)
DBA/2J ENSMUSG00185036138
 protein coding gene Chr14:27375554-27416301 (-)
FVB/NJ ENSMUSG00205020337
 protein coding gene Chr14:22965157-23006033 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230032345
 protein coding gene Chr14:34656328-34696504 (-)
NOD/ShiLtJ ENSMUSG00190016219
 protein coding gene Chr14:23119698-23160544 (-)
NZO/HlLtJ ENSMUSG00225035929
 protein coding gene Chr14:28994391-29035237 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    UQCC5, ubiquinol-cytochrome c reductase complex assembly factor 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UQCC5, ubiquinol-cytochrome c reductase complex assembly factor 5
  • Synonyms
    C3orf78, SMIM4
  • Links
    NCBI Gene ID: 440957
    UniProt: Q8WVI0

  • Chr Location
    3p21.1; chr3:52533950-52579237 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66487 NCBI Gene Model | MGI Sequence Detail 40814 C57BL/6J ±  kb
transcript NM_001308466 RefSeq | MGI Sequence Detail 1350 C57BL/6  
polypeptide Q8C1Q6 UniProt | EBI | MGI Sequence Detail 80 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000059980 ubiquinol-cytochrome c reductase complex assembly factor 5
    (term hierarchy)
  • InterPro Domains
    IPR028183 Ubiquinol-cytochrome-c reductase complex assembly factor 5
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:5624007, MGI:7380600
References
more
  • Summaries
    All 26
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:330815 Liang C, et al., Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis. Cell Rep. 2022 Aug 16;40(7):111204
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory