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Tmem177 Gene Detail
Summary
  • Symbol
    Tmem177
  • Name
    transmembrane protein 177
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913593
    NCBI Gene: 66343
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:119835620-119840913 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 52.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    196 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913593
 protein coding gene Chr1:119835620-119840938 (-)
129S1/SvImJ ENSMUSG00200001601
 protein coding gene Chr1:117312198-117317515 (-)
A/J ENSMUSG00195004153
 protein coding gene Chr1:116552985-116558302 (-)
AKR/J ENSMUSG00220024108
 protein coding gene Chr1:116368710-116374027 (-)
BALB/cJ ENSMUSG00180012192
 protein coding gene Chr1:116962608-116967925 (-)
C3H/HeJ ENSMUSG00175019094
 protein coding gene Chr1:116783837-116789154 (-)
C57BL/6NJ ENSMUSG00215010568
 protein coding gene Chr1:116742791-116748109 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014516
 protein coding gene Chr1:111936028-111941352 (-)
CAST/EiJ ENSTCUG00005006422
 protein coding gene Chr1:115717117-115722425 (-)
CBA/J ENSMUSG00210001044
 protein coding gene Chr1:116613476-116618793 (-)
DBA/2J ENSMUSG00185013364
 protein coding gene Chr1:121061814-121067131 (-)
FVB/NJ ENSMUSG00205011549
 protein coding gene Chr1:116115829-116121147 (-)
JF1/MsJ ENSUMUG00000025806
 protein coding gene Chr1:120154489-120159789 (-)
LP/J ENSMUSG00230008800
 protein coding gene Chr1:120490004-120495321 (-)
NOD/ShiLtJ ENSMUSG00190006078
 protein coding gene Chr1:116598689-116604006 (-)
NZO/HlLtJ ENSMUSG00225004476
 protein coding gene Chr1:124284394-124289710 (-)
PWK/PhJ ENSLUMG00010014015
 protein coding gene Chr1:115740086-115745386 (-)
SPRET/EiJ ENSMSPG00010016245
 protein coding gene Chr1:118374205-118376463 (-)
WSB/EiJ ENSIUOG00005002967
 protein coding gene Chr1:116465266-116470584 (-)



Homology
more
  • Human Ortholog
    TMEM177, transmembrane protein 177
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM177, transmembrane protein 177
  • Links
    NCBI Gene ID: 80775
    UniProt: Q53S58

  • Chr Location
    2q14.2; chr2:119679137-119723618 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    4
  • cDNA Data
    25
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66343 NCBI Gene Model | MGI Sequence Detail 5294 C57BL/6J ±  kb
transcript NM_175106 RefSeq | MGI Sequence Detail 3316 C57BL/6  
polypeptide Q8BPE4 UniProt | EBI | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory